Efficacy of Hormonal Therapy Versus Surgical Correction in Adult Cryptorchidism Long-Term Outcomes of Microsurgical Producers

Muhammad Musa Kakar; Durdana Mohsin; Asadullah; Ali Nawaz; Sana Ullah Kakar

doi:10.70749/ijbr.v3i2.2444

Authors

Muhammad Musa Kakar Department of Urology, Sandeman Provincial Hospital (SPH) & Bolan Medical College (BMC), Quetta, Balochistan, Pakistan.
Durdana Mohsin Department of Surgery, Jhalawan Medical College, Khuzdar, Balochistan, Pakistan.
Asadullah Department of Urology, Sandeman Provincial Hospital (SPH) & Bolan Medical College (BMC), Quetta, Balochistan, Pakistan.
Ali Nawaz Department of Urology, Sandeman Provincial Hospital (SPH) & Bolan Medical College (BMC), Quetta, Balochistan, Pakistan.
Sana Ullah Kakar Balochistan Institute of Psychiatry and Behavioral Sciences (BIPBS), Quetta, Balochistan, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i2.2444

Keywords:

Efficacy, Hormonal Therapy, Surgical Correction, Adult Cryptorchidism, Microsurgical Outcomes, Long-term Results.

Abstract

Background: Infertility and psychological discomfort in adult males are still largely caused by cryptorchidism, which is the lack of one or both testes to descend into the scrotum. Hormonal therapy and surgical correction are two possible treatments; however, it is unclear how effective either is in adults. Objective: The purpose of this study was to assess the efficacy of microsurgical correction and hormone therapy for adult cryptorchidism, with an emphasis on long-term results concerning testicular descent, patient satisfaction, and reproductive potential. Methodology: 150 adult patients with cryptorchidism who were purposefully chosen from a tertiary care hospital's urology and andrology departments participated in a qualitative study. Semi-structured interviews and clinical record analysis were used to gather data, which examined testicular descent, psychological effects, fertility outcomes, demographic information, and the type of intervention. The results were interpreted and the two therapy modalities were compared using thematic analysis. Results: The majority of the 150 participants were between the ages of 20 and 40, and unilateral engagement predominated. Compared to 28% of individuals in the hormonal group, 88% of patients treated with microsurgery experienced complete testicular descent. In surgical cases, testicular atrophy was 6.7%, but in hormonal situations, it was 18.7%. Compared to hormonal therapy (30.7%), patient satisfaction was much higher following surgery (84%). Additionally, improved body image and fewer problems, including psychological anguish and recurrence, were noted by surgery patients. Conclusion: When it came to treating adult cryptorchidism, microsurgical correction outperformed hormonal therapy by providing better results in terms of testicular descent, reproductive potential, and psychological well-being. Surgery should be regarded as the recommended course of treatment for adult patients, as hormonal therapy showed little success and increased relapse rates. Reproductive and emotional results can be significantly enhanced by early diagnosis and prompt surgical intervention.

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