Outcome of Minimally Invasive Spine Surgery for Degenerative Spine Disease in Tertiary Care Hospital
DOI:
https://doi.org/10.70749/ijbr.v3i6.2446Keywords:
Minimally Invasive Spine Surgery, Degenerative Spine Disease, Lumbar Disc Herniation, Spinal Stenosis, Spondylolisthesis, Neurological Recovery, Tertiary Care Hospital.Abstract
Background: Degenerative spine disease is a common cause of chronic pain and disability, often requiring surgical intervention when conservative measures fail. Minimally invasive spine surgery (MISS) has gained prominence as an alternative to open procedures, with the aim of reducing morbidity while achieving similar or superior outcomes. Objective: The purpose of this study was to evaluate the clinical and functional outcomes of MISS in patients with degenerative spinal disorders treated at a tertiary care hospital. Methods: A prospective observational study was conducted on 67 patients who underwent MISS between February 2024 and February 2025. Clinical data, operative parameters, complications, and follow-up outcomes were recorded. Pain and disability were measured using the Visual Analog Scale (VAS) and Oswestry Disability Index (ODI), respectively. Statistical analysis was performed to compare pre- and postoperative scores, with p < 0.05 considered significant. Results: The mean age of the patients was 52.8 years, with a male-to-female ratio of 1.4:1. Lumbar disc herniation (43.3%) was the most common pathology, followed by spinal stenosis (37.3%) and spondylolisthesis (19.4%). The mean operative time was 112 minutes, and mean blood loss was 126 ml. Conversion to open surgery occurred in 3% of cases. Pain scores improved significantly from 7.2 to 2.1 (p < 0.001), and ODI decreased from 58.4% to 18.7% (p < 0.001) at six months. Neurological recovery was observed in 85.7% of patients with baseline deficits. Complication rates were low, with infections in 4.5% and reoperations in 3%. Conclusion: MISS is a safe and effective surgical option for degenerative spine disease, offering significant improvements in pain, disability, and neurological recovery, with low complication rates. The results support its role as a reliable alternative to open procedures in tertiary care practice.
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1. Yolcu, Y. U., Helal, A., Alexander, A. Y., Bhatti, A. U., Alvi, M. A., Abode-Iyamah, K., & Bydon, M. (2021). Minimally invasive versus open surgery for degenerative spine disorders for elderly patients: Experiences from a single institution. World Neurosurgery, 146, e1262-e1269.
https://doi.org/10.1016/j.wneu.2020.11.145
2. Sharma, A., Shakya, A., Singh, V., Deepak, P., Mangale, N., Jaiswal, A., & Marathe, N. (2022). Incidence of dural tears in open versus minimally invasive spine surgery: A single-center prospective study. Asian Spine Journal, 16(4), 463-470.
https://doi.org/10.31616/asj.2021.0140
3. Carroll, A. H., Dowlati, E., Molina, E., Zhao, D., Altshuler, M., Mueller, K. B., Sandhu, F. A., & Voyadzis, J. (2021). Does minimally invasive spine surgery improve outcomes in the obese population? A retrospective review of 1442 degenerative lumbar spine surgeries. Journal of Neurosurgery: Spine, 35(4), 460-470.
https://doi.org/10.3171/2021.1.spine201785
4. Wang, M. Y., Park, P., Tran, S., Anand, N., Nunley, P., Kanter, A., Fessler, R., Uribe, J., Eastlack, R., Shaffrey, C. I., Bess, S., Mundis, G. M., Brusko, G. D., & Mummaneni, P. V. (2020). Intermediate-term clinical and radiographic outcomes with less invasive adult spinal deformity surgery: Patients with a minimum follow-up of 4 years. Acta Neurochirurgica, 162(6), 1393-1400.
https://doi.org/10.1007/s00701-020-04320-x
5. Heemskerk, J., Akinduro, O., Clifton, W., Hinojosa, A., & Abode-Iyamah, K. (2019). Long-term clinical outcome of minimally invasive versus open single-level transforaminal lumbar interbody fusion for degenerative lumbar diseases with a minimum follow-up of 2 years: A meta-analysis protocol. Journal of Neuroscience and Neurological Disorders, 3(2), 091-095.
https://doi.org/10.29328/journal.jnnd.1001021
6. Singh, P., Amitkumar, M., Singh, K., Khumukcham, T., Sawarkar, D., Chandra, S., & Kale, S. (2020). Surgical outcome in spinal operation in patients aged 70 years and above. Neurology India, 68(1), 45.
https://doi.org/10.4103/0028-3886.279672
7. Pokorny, G., Amaral, R., Marcelino, F., Moriguchi, R., Barreira, I., Yozo, M., & Pimenta, L. (2022). Minimally invasive versus open surgery for degenerative lumbar pathologies:a systematic review and meta-analysis. European Spine Journal, 31(10), 2502-2526.
https://doi.org/10.1007/s00586-022-07327-3
8. Ramanathan, S., Rapp, A., Perez-Cruet, M., & Fahim, D. K. (2023). Long-term Reoperation rates after open versus minimally invasive spine surgery for degenerative lumbar disease: Five year follow-up of 2130 patients. World Neurosurgery, 171, e126-e136.
https://doi.org/10.1016/j.wneu.2022.11.100
9. Ao, S., Zheng, W., Wu, J., Tang, Y., Zhang, C., Zhou, Y., & Li, C. (2020). Comparison of preliminary clinical outcomes between percutaneous endoscopic and minimally invasive transforaminal lumbar interbody fusion for lumbar degenerative diseases in a tertiary hospital: Is percutaneous endoscopic procedure superior to MIS-TLIF? A prospective cohort study. International Journal of Surgery, 76, 136-143.
https://doi.org/10.1016/j.ijsu.2020.02.043
10. Sinha, J., Kankane, V. K., Shukla, A., & Sharma, A. (2023). Clinical and functional outcomes of open versus minimally invasive surgeries in single-level prolapsed intervertebral disc in lumbar region at tertiary care center: A prospective study. Asian Journal of Medical Sciences, 14(9), 265-269.
https://doi.org/10.3126/ajms.v14i9.53661
11. Khan, M. I., Munir, A., Aziz, S., Ali, H., Shah, S. M., & Nasir, F. (2023). Short term clinical outcomes in spine surgeries. A descriptive cross sectional study in a tertiary care hospital. Pakistan Journal of Medical and Health Sciences, 17(5), 613-616.
https://doi.org/10.53350/pjmhs2023175613
12. Chan, A. K., Bisson, E. F., Bydon, M., Glassman, S. D., Foley, K. T., Shaffrey, C. I., Potts, E. A., Shaffrey, M. E., Coric, D., Knightly, J. J., Park, P., Wang, M. Y., Fu, K., Slotkin, J. R., Asher, A. L., Virk, M. S., Kerezoudis, P., Alvi, M. A., Guan, J., … Mummaneni, P. V. (2020). Predictors of the best outcomes following minimally invasive surgery for grade 1 degenerative lumbar spondylolisthesis. Neurosurgery, 87(6), 1130-1138.
https://doi.org/10.1093/neuros/nyaa206
13. Kim, H., Wu, P., Raorane, H., & Jang, I. (2020). Generation change of practice in spinal surgery: Can endoscopic spine surgery expand its indications to fill in the role of conventional open spine surgery in most of degenerative spinal diseases and disc Herniations: A study of 616 spinal cases 3 years. Neurology India, 68(5), 1157.
https://doi.org/10.4103/0028-3886.299145
14. Klimov, V., Evsyukov, A., Amelina, E., Ryabykh, S., & Simonovich, A. (2022). Predictors of complications and unfavorable outcomes of minimally invasive surgery treatment in elderly patients with degenerative lumbar spine pathologies (Case series). Frontiers in Surgery, 9.
https://doi.org/10.3389/fsurg.2022.869345
15. Bovonratwet, P., Samuel, A. M., Mok, J. K., Vaishnav, A. S., Morse, K. W., Song, J., Steinhaus, M. E., Jordan, Y. J., Gang, C. H., & Qureshi, S. A. (2022). Minimally invasive lumbar decompression versus minimally invasive Transforaminal lumbar Interbody fusion for treatment of low-grade lumbar degenerative spondylolisthesis. Spine, 47(21), 1505-1514.
https://doi.org/10.1097/brs.0000000000004432
16. Lak, A. M., Abunimer, A. M., Rahimi, A., Tafel, I., Chi, J., Lu, Y., Groff, M., & Zaidi, H. A. (2020). Outcomes of minimally invasive versus open surgery for intermediate to high-grade spondylolisthesis. Spine, 45(20), 1451-1458.
https://doi.org/10.1097/brs.0000000000003573
17. Mai, D., Brand, C., Haschtmann, D., Pirvu, T., Fekete, T. F., & Mannion, A. F. (2019). Non-medical factors significantly influence the length of hospital stay after surgery for degenerative spine disorders. European Spine Journal, 29(2), 203-212.
https://doi.org/10.1007/s00586-019-06209-5
18. Silva, P. S., Jardim, A., Pereira, J., Sousa, R., Vaz, R., & Pereira, P. (2023). Minimally invasive fusion surgery for patients with degenerative spondylolisthesis and severe lumbar spinal stenosis: A comparative study between MIDLIF and TLIF. European Spine Journal, 32(9), 3210-3217.
https://doi.org/10.1007/s00586-023-07847-6
19. Weir, T. B., Sardesai, N., Jauregui, J. J., Jazini, E., Sokolow, M. J., Usmani, M. F., Camacho, J. E., Banagan, K. E., Koh, E. Y., Kurtom, K. H., Davis, R. F., Gelb, D. E., & Ludwig, S. C. (2019). Effect of surgical setting on hospital-reported outcomes for elective lumbar spinal procedures: Tertiary versus community hospitals. Global Spine Journal, 10(4), 375-383.
https://doi.org/10.1177/2192568219848666
20. Chou, D., Lafage, V., Chan, A. Y., Passias, P., Mundis, G. M., Eastlack, R. K., Fu, K., Fessler, R. G., Gupta, M. C., Than, K. D., Anand, N., Uribe, J. S., Kanter, A. S., Okonkwo, D. O., Bess, S., Shaffrey, C. I., Kim, H. J., Smith, J. S., Sciubba, D. M., … _, _. (2022). Patient outcomes after circumferential minimally invasive surgery compared with those of open correction for adult spinal deformity: Initial analysis of prospectively collected data. Journal of Neurosurgery: Spine, 36(2), 203-214.
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