Frequency of Sensory Neuropathy in patients with Long Standing Diabetes Presenting to Abbottabad Medical Complex
DOI:
https://doi.org/10.70749/ijbr.v3i7.2589Keywords:
Sensory neuropathy, diabetes mellitus, glycemic control, peripheral neuropathy, PakistanAbstract
Diabetic sensory neuropathy remains one of the most common and disabling complications of long-standing diabetes mellitus, contributing substantially to morbidity, functional impairment, and reduced quality of life. This cross-sectional study aimed to determine the frequency and associated factors of sensory neuropathy among patients with long-standing diabetes presenting to the Medicine Department of Abbottabad Medical Complex. A total of 113 patients aged 30–70 years with diabetes duration exceeding five years were enrolled over six months (17 November 2024 to 17 May 2025). Sensory neuropathy was assessed clinically using predefined criteria, including numbness, paresthesia, impaired vibration sense, and reduced proprioception. Data were analyzed using SPSS version 25.0. The average age of the group was 54.8 8.6 years, and 52.2 percent of the group was male. The total occurrence of sensory neuropathy was 41.6 (n = 47). Diabetes duration more than 10 years old (p = 0.01) and weak glycemic control (p = 0.02) were significantly linked with neuropathy. Greater BMI, rurality, and anemia presented greater percentages of neuropathy, but not statistically significant. Numbness (83%), tingling or paresthesia (72.3%), and loss of sense of vibration (59.6) were the most common symptoms. The findings indicate the significant contribution of diabetic sensory neuropathy to the patients with long-standing diabetes in north Pakistan. Their close relation with poor glycemic management and extended disease course explains the necessity of regular neurological examination and precautionary actions. Organized screening evaluating neuropathy might improve patient functional outcomes, lessen long-term disability, and enhance patient quality of life which in turn strengthens diabetes care.
Downloads
References
1. Alamri A, Alharbi K, Hassan K, Alhakami S, Alosaimi M, Rafidi K, et al. (2021). Frequency of neuropathic sensory symptoms among patients with uncontrolled diabetes mellitus at Security Forces Hospital, Riyadh, Saudi Arabia. Cureus, 13(8), e17528.
https://doi.org/10.7759/cureus.17528
2. Hossain, M. J., Al‐Mamun, M., & Islam, M. R. (2024). Diabetes mellitus, the fastest growing global public health concern: Early detection should be focused. Health Science Reports, 7(3), e2004.
https://doi.org/10.1002/hsr2.2004
3. Verma, A. K., Goyal, Y., Bhatt, D., Dev, K., Alsahli, M. A., Rahmani, A. H., & Almatroudi, A. (2021). A compendium of perspectives on diabetes: a challenge for sustainable health in the modern era. Diabetes, metabolic syndrome and obesity, 2775-2787.
https://doi.org/10.2147/dmso.s304751
4. Aloke, C., Egwu, C. O., Aja, P. M., Obasi, N. A., Chukwu, J., Akumadu, B. O., ... & Achilonu, I. (2022). Current advances in the management of diabetes mellitus. Biomedicines, 10(10), 2436.
https://doi.org/10.3390/biomedicines10102436
5. Saeedi P, Petersohn I, Salpea P, et al. (2019). Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition. Diabetes Research and Clinical Practice, 157, 107843.
https://doi.org/10.1016/j.diabres.2019.107843
6. Jwad S.M., Al-Fatlawi H.Y. (2022). Types of diabetes and their effect on the immune system. Journal of Advanced Pharmacy Practice, 4, 21–30.
7. Zilliox L.A. (2021). Diabetes and peripheral nerve disease. Clinics in Geriatric Medicine, 37(2), 253–267.
https://doi.org/10.1016/j.cger.2020.12.001
8. Oztorun H.S., Gozukara B., Bahi R., Turgut T., Sürmeli D.M., Çoarderelioglu C., et al. (2022). A higher incidence of diabetic peripheral neuropathy may be associated with decreased sleep and increased depression in older adults. Journal of Health Science and Medicine, 5(4), 1162–1169.
https://doi.org/10.32322/jhsm.1133659
9. Sloan, G., Selvarajah, D., & Tesfaye, S. (2021). Pathogenesis, diagnosis and clinical management of diabetic sensorimotor peripheral neuropathy. Nature Reviews Endocrinology, 17(7), 400-420.
https://doi.org/10.1038/s41574-021-00496-z
10. Galiero, R., Caturano, A., Vetrano, E., Beccia, D., Brin, C., Alfano, M., ... & Sasso, F. C. (2023). Peripheral neuropathy in diabetes mellitus: pathogenetic mechanisms and diagnostic options. International Journal of Molecular Sciences, 24(4), 3554.
https://doi.org/10.3390/ijms24043554
11. Strand, N., Anderson, M. A., Attanti, S., Gill, B., Wie, C., Dawodu, A., ... & Maloney, J. A. (2024). Diabetic neuropathy: pathophysiology review. Current pain and headache reports, 28(6), 481-487.
https://doi.org/10.1007/s11916-024-01243-5
12. Hussain A., Ahmad I., Khan M.N., Zar A., Shahzad S. (2021). Peripheral neuropathy among patients with type 2 diabetes using Michigan Neuropathy Screening Instrument. Journal of Postgraduate Medical Institute, 35(1), 7–11.
https://doi.org/10.54079/jpmi.35.1.2735
13. Anandhanarayanan, A., Teh, K., Goonoo, M., Tesfaye, S., & Selvarajah, D. (2022). Diabetic neuropathies. Endotext [Internet].
14. Jensen, T. S., Karlsson, P., Gylfadottir, S. S., Andersen, S. T., Bennett, D. L., Tankisi, H., ... & Callaghan, B. C. (2021). Painful and non-painful diabetic neuropathy, diagnostic challenges and implications for future management. Brain, 144(6), 1632-1645.
https://doi.org/10.1093/brain/awab079
15. Abdelhafiz, A. H., & Sinclair, A. J. (2022). Diabetic neuropathy. Pathy's Principles and Practice of Geriatric Medicine, 1, 698-708.
https://doi.org/10.1002/9781119484288.ch55
16. Akhtar S., Hassan F., Saqlain S.R., Ali A., Hussain S. (2023). The prevalence of peripheral neuropathy among patients with diabetes in Pakistan: A systematic review and meta-analysis. Scientific Reports, 13, 11744.
https://doi.org/10.1038/s41598-023-39037-1
17. Iqbal S., Mehr M.T., Ullah N. (2022). Frequency of sensory neuropathy and its correlation with type and duration of diabetes in patients with diabetic foot ulcer: A cross-sectional study at a tertiary care hospital. Northwest Journal of Medical Sciences, 2(4), 25–32.
https://doi.org/10.69723/njms.02.04.0353
18. Perveen, W., Ahsan, H., Shahzad, R., Fayyaz, S., Zaif, A., Paracha, M. A., ... & Alghadir, A. H. (2024). Prevalence of peripheral neuropathy, amputation, and quality of life in patients with diabetes mellitus. Scientific Reports, 14(1), 14430.
https://doi.org/10.1038/s41598-024-65495-2
19. Asghar, S., Ali, Z., Abdullah, A., Naveed, S., Ahmad, M. S., & Rafi, T. S. M. (2024). Sensorineural hearing loss among type 2 diabetic patients and its association with peripheral neuropathy: a cross-sectional study from a lower middle-income country. BMJ open, 14(5), e081035.
https://doi.org/10.1136/bmjopen-2023-081035
20. Sulehria S.B., Ullah S., Hussain N., Ullah A., Ullah H. (2022). Frequency of large-fibre sensory neuropathy in diabetes mellitus and comparison of hand grip strength in patients with and without large-fibre sensory neuropathy. Pakistan Journal of Medical and Health Sciences, 2022.
https://doi.org/10.53350/pjmhs22167183
21. Beshyah, S. A., Jayyousi, A., Al-Mamari, A. S., Shaaban, A., Ozairi, E. A., Nafach, J., ... & Evans, M. (2024). Current perspectives in pre-and diabetic peripheral neuropathy diagnosis and management: an expert statement for the gulf region. Diabetes Therapy, 15(12), 2455-2474.
https://doi.org/10.1007/s13300-024-01658-8
22. Anastasi, J. K., & Capili, B. (2022). Detecting peripheral neuropathy in patients with diabetes, prediabetes and other high-risk conditions: an advanced practice nurse’s perspective. Journal of medical & clinical nursing, 3(2), 143.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Indus Journal of Bioscience Research

This work is licensed under a Creative Commons Attribution 4.0 International License.
