Volatile Anesthetics Maintain Tidal Volume and Minute Ventilation to a Greater Degree than Propofol under Spontaneous Respiration

Muhammad Shahzad Aslam Khan; Humayun Munir; Mishkatullah; Junaid Zafar; Hafiz Moeen ud Din; Huma Nawab

doi:10.70749/ijbr.v3i1.481

Authors

Muhammad Shahzad Aslam Khan Department of Anaesthesia, Pak Emirates Military Hospital, Rawalpindi, Punjab, Pakistan.
Humayun Munir Department of Anaesthesia, Pak Emirates Military Hospital, Rawalpindi, Punjab, Pakistan.
Mishkatullah Department of Orthopedic, Combined Military Hospital, Rawalpindi, Punjab, Pakistan.
Junaid Zafar Department of Anaesthesia and Critical Care Medicine, Combined Military Hospital, Multan, Punjab, Pakistan.
Hafiz Moeen ud Din Department of Anaesthesia, Pak Emirates Military Hospital, Rawalpindi, Punjab, Pakistan.
Huma Nawab Department of Obstetrics and Gynaecology, Pakistan Institute Medical Sciences, Islamabad, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i1.481

Keywords:

Volatile Anesthetics, Propofol, Tidal Volume, Minute Ventilation, Spontaneous Respiration, Anesthesia, Respiratory Function, Patient Safety

Abstract

Background: Anesthesia is one of the most fundamental aspects of today’s medicine, without which surgeries cannot be performed safely and with minimal pain. Various anesthetic drugs; volatile agents; sevoflurane, isoflurane, desflurane and intravenous agents; propofol effects respiratory functions like tidal volume and frequency or minute volume. Such effects should not be overlooked due to the frequent reliance on reports of patients in which spontaneous respiration is paramount. Aim: is to control spontaneous respiration to evaluate which of the two agents; volatile anesthetic or propofol, is most efficient in maintaining tidal volume and minimum ventilation. Methodology: The study was conducted at Pak Emirates Military Hospital, Rawalpindi, Pakistan, and used a prospective observational cohort, whereby a set of anesthetic agents was given to a group of patients. Relaxation and tidal volume together with the minute ventilation were assessed during spontaneous breathing during volatile anesthetics and propofol effect. Primary outcomes, with regard to respiratory parameters, were compared between the two anesthetic groups to determine if statistical differences exist. Results: The results established that the volatile anesthetics were significantly more superior to propofol in enhancing both tidal volume and MV during spontaneous breathing. Based on these studies, the present results showed that the steady anesthetic agents possess a greater potential for a respiratory dial in the potential situations involving spontaneous breathing compared to propofol. Conclusion: Compared to propofol, volatile anesthetics can more effectively kept tidal volume and minute ventilation at spontaneous respiration thus apparently give better results in clinical settings where respiratory function is paramount. Such outcomes may help anesthesiologists to choose the proper agents in order to achieve improved patients’ results, especially in cases where spontaneous breathing should be maintained.

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