Evaluating the Effect of Honey as a Natural Remedy for the Management of Sore Throat

Authors

  • Muhammad Hamza Department of Nutritional Sciences, Government College University Faisalabad, Punjab, Pakistan.
  • Zahin Anjum Department of Food and Nutrition Sciences, CHE, University of Peshawar, KPK, Pakistan.
  • Rameesha Department of Nutritional Sciences, Government College University Faisalabad, Punjab, Pakistan
  • Fatima Department of Zoology, Ghazi University, D.G. Khan, Punjab, Pakistan.
  • Memoona Fatima Department of Public Health and Nutrition, University of Haripur, KPK, Pakistan.
  • Ayesha Faculty of Nutrition Sciences, The University of Agriculture, Peshawar, KPK, Pakistan.
  • Aisha Institute of Food Science and Nutrition, University of Sargodha, Punjab, Pakistan.
  • Sadaf Department of Nutritional Sciences, Government College University Faisalabad, Punjab, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v2i02.106

Keywords:

Honey, Sore throat, ENT, Anti-inflammatory, Antimicrobial, Natural remedy, Complementary therapy

Abstract

Background: Sore throat is the most common condition in patients suffering with tonsillitis, allergies, sinus drainage as well as viral or bacterial infections. Conventional treatments of sore throat include antibiotics, lozenges and pain relievers but now-a-days, there is an increasing trend to use natural remedies, because of the side effects of antibiotics such as antibiotic resistance. This systematic review examines the effectiveness of honey as a natural therapy for the management of sore throat.

Objective: The main objective of the study was to systematically review the supporting evidence regarding the use, effectiveness and potential mechanism of honey as natural remedy for managing the sore throat.

Methods: A systematic literature review was conducted from databases like, Google Scholar, PubMed, as well as Science Direct, to collect relevant studies regarding the use of honey as a remedy for the management of sore throat. The search was conducted using keywords like "sore throat," "honey," "pharyngitis," "anti-inflammatory," and "antimicrobial." Studies including comparative effectiveness with other natural remedies were also considered.

Results: Studies demonstrates that honey exert a significant impact to relieve symptoms of sore throat such as soothing the tissue irritation as well as pain reduction. Honey has antimicrobial and anti-inflammatory properties that ultimately contributes to its effectiveness in managing the viral and bacterial infections. Many studies also highlight the role of honey in coating the throat as well as promoting the hydration.

Conclusion: Honey is an easily available product in the household, having anti-microbial, anti-inflammatory as well as antioxidant properties. Studies shows that honey is a best remedy to reduce the fever, pain, as well as oropharyngeal congestions. Moreover, there is no resistance of side effects on the intake of honey, thereby considered a safe treatment method. However, the consistency and quality of honey, dosage variations, as well as limited large-scale clinical trials highlights that there is a still need to conduct various researches

Downloads

Download data is not yet available.

References

Middleton DB. Pharyngitis. Primary Care: Clinics in Office Practice. 1996 Dec 1;23(4):719-39.

Tanz RR. Sore throat. Nelson pediatric symptom-based diagnosis. 2018:1.

Perry M. The Throat: Part II-Inflammation, Infections and the acutely painful throat. Diseases and Injuries to the Head, Face and Neck: A Guide to Diagnosis and Management. 2021:1359-408.

Chan TV. The patient with sore throat. Medical Clinics. 2010 Sep 1;94(5):923-43.

Weckmann G, Hauptmann‐Voß A, Baumeister SE, Kloetzer C, Chenot JF. Efficacy of AMC/DCBA lozenges for sore throat: A systematic review and meta‐analysis. International Journal of Clinical Practice. 2017 Oct;71(10):e13002.

Kishore N, Kumar P, Shanker K, Verma AK. Human disorders associated with inflammation and the evolving role of natural products to overcome. European journal of medicinal chemistry. 2019 Oct 1;179:272-309.

Almasaudi S. The antibacterial activities of honey. Saudi journal of biological sciences. 2021 Apr 1;28(4):2188-96.

Kumar R, Kumar S, Kanwar SS. Biomederspectives of Herbal Honey. InBiomedical Perspectives of Herbal Honey 2024 Apr 25 (pp. 89-167). Singapore: Springer Nature Singapore.

Bogdanov S, Jurendic T, Sieber R, Gallmann P. Honey for nutrition and health: a review. Journal of the American college of Nutrition. 2008 Dec 1;27(6):677-89.

Cozzolino D, Corbella E, Smyth HE. Quality control of honey using infrared spectroscopy: a review. Applied Spectroscopy Reviews. 2011 Oct 1;46(7):523-38.

Cooper R, Molan P. The use of honey as an antiseptic in managing Pseudomonas infection. Journal of wound care. 1999 Apr;8(4):161-4.

Hasam S, Qarizada D, Azizi M. A review: honey and its nutritional composition. Asian Journal of Research in Biochemistry. 2020;7(3):34-43.

S. Baba, B.E.N. Dauda, S. Mustapha and N.O. Adeosun, 2020. Proximate, Physicochemical and Antimicrobial Analysis of Honey Produced by Apis mellifera and Meliponula ferruginea. Singapore Journal of Scientific Research, 10: 221-228.

Lusby PE, Coombes AL, Wilkinson JM. Bactericidal activity of different honeys against pathogenic bacteria. Archives of medical research. 2005 Sep 1;36(5):464-7.

Jiang X, Lin A, Li S, Shi Y, Zhou F, Felix Gomez GG, Gregory RL, Zhang C, Chen S, Huang R. Effects of artificial honey and epigallocatechin-3-gallate on streptococcus pyogenes. BMC microbiology. 2022 Aug 26;22(1):207.

Kuchar E, Miśkiewicz K, Nitsch-Osuch A, Szenborn L. Pathophysiology of clinical symptoms in acute viral respiratory tract infections. Pulmonary Infection. 2015:25-38.

Keane MP, Strieter RM. Chemokine signaling in inflammation. Critical care medicine. 2000 Apr 1;28(4):N13-26.

Yang D, Elner SG, Bian ZM, Till GO, Petty HR, Elner VM. Pro-inflammatory cytokines increase reactive oxygen species through mitochondria and NADPH oxidase in cultured RPE cells. Experimental eye research. 2007 Oct 1;85(4):462-72.

Schieber M, Chandel NS. ROS function in redox signaling and oxidative stress. Current biology. 2014 May 19;24(10):R453-62.

Levy ML, Ericsson CD, Pickering LK. Infections of the upper respiratory tract. Medical Clinics of North America. 1983 Jan 1;67(1):153-71.

Vani V, Pai PS, Srilakshmi R, Srilatha R, Menon S. SYNERGISTIC ANTIBACTERIAL ACTIVITY OF HONEY AND ANTIBIOTICS AGAINST COMMON UPPER RESPIRATORY TRACT MICROFLORA.

Al-Waili NS, Salom K, Butler G, Al Ghamdi AA. Honey and microbial infections: a review supporting the use of honey for microbial control. Journal of medicinal food. 2011 Oct 1;14(10):1079-96.

Luca L, Pauliuc D, Oroian M. Honey microbiota, methods for determining the microbiological composition and the antimicrobial effect of honey–A review. Food Chemistry: X. 2024 Jun 4:101524.

Gheldof N, Wang XH, Engeseth NJ. Identification and quantification of antioxidant components of honeys from various floral sources. Journal of agricultural and food chemistry. 2002 Oct 9;50(21):5870-7.

Aljadi AM, Yusoff KM. Isolation and identification of phenolic acids in Malaysian honey with antibacterial properties. Turkish Journal of Medical Sciences. 2003;33(4):229-36.

Brudzynski K, Abubaker K, Miotto D. Unraveling a mechanism of honey antibacterial action: Polyphenol/H2O2-induced oxidative effect on bacterial cell growth and on DNA degradation. Food chemistry. 2012 Jul 15;133(2):329-36.

Mavric E, Wittmann S, Barth G, Henle T. Identification and quantification of methylglyoxal as the dominant antibacterial constituent of Manuka (Leptospermum scoparium) honeys from New Zealand. Molecular nutrition & food research. 2008 Apr;52(4):483-9.

Packer JM, Irish J, Herbert BR, Hill C, Padula M, Blair SE, Carter DA, Harry EJ. Specific non-peroxide antibacterial effect of manuka honey on the Staphylococcus aureus proteome. International journal of antimicrobial agents. 2012 Jul 1;40(1):43-50.

Pasupuleti VR, Sammugam L, Ramesh N, Gan SH. Honey, propolis, and royal jelly: a comprehensive review of their biological actions and health benefits. Oxidative medicine and cellular longevity. 2017;2017(1):1259510.

Mushtaq S, Imtiyaz Z, Wali AF, Khan A, Rashid SM, Amin I, Ali A, Rehman MU, Arafah A. Honey: A Powerful Natural Antioxidant and Its Possible Mechanism of Action. Therapeutic Applications of Honey and its Phytochemicals: Vol. 1. 2020:11-29.

El-Seedi HR, Eid N, Abd El-Wahed AA, Rateb ME, Afifi HS, Algethami AF, Zhao C, Al Naggar Y, Alsharif SM, Tahir HE, Xu B. Honey bee products: preclinical and clinical studies of their anti-inflammatory and immunomodulatory properties. Frontiers in Nutrition. 2022 Jan 3;8:761267.

Idris UA, Tijjani MB, Aliyu MS. Evaluation of synergetic activity of honey and ginger extracts on Pseudomonas aeruginosa and Methicillin-Resistant Staphylococcus aureus. UMYU Journal of Microbiology Research (UJMR). 2016 Dec 30;1(1):152-60.

Ballester P, Cerdá B, Arcusa R, Marhuenda J, Yamedjeu K, Zafrilla P. Effect of ginger on inflammatory diseases. Molecules. 2022 Oct 25;27(21):7223.

Ghosh N, Ali A, Ghosh R, Das S, C Mandal S, Pal M. Chronic inflammatory diseases: progress and prospect with herbal medicine. Current Pharmaceutical Design. 2016 Jan 1;22(2):247-64.

Kumar S, Verma M, Hajam YA, Kumar R. Honey infused with herbs: A boon to cure pathological diseases. Heliyon. 2024 Jan 1.

Bachynski M. Nature's Cure: Healing the Body with Herbal Remedies. eBookIt. com; 2024 Mar 27.

Jaybhaye DL, Chandra S, Johar S, Nagre AS. Effect of honey and ginger mixture on productive cough in pediatrics patients. International Journal of Basic & Clinical Pharmacology. 2022 May;11(3):237.

Downloads

Published

2024-10-19

How to Cite

Evaluating the Effect of Honey as a Natural Remedy for the Management of Sore Throat. (2024). Indus Journal of Bioscience Research, 2(02), 37-41. https://doi.org/10.70749/ijbr.v2i02.106