Frequency of Preterm Labour in Women Attending Delivery Suite of Civil Hospital, Karachi

Authors

  • Ayesha Sami Department of Obstetrics and Gynaecology, MBBS Civil Hospital, Karachi, Sindh, Pakistan.
  • Misbah Harim Liaquat Institute of Medical Health Sciences, Thatta Campus, Sindh, Pakistan.
  • Nadia Ali Department of Obstetrics and Gynaecology, MBBS Civil Hospital, Karachi, Sindh, Pakistan.
  • Aneeta Department of Obstetrics and Gynaecology, Dr Ruth KM Pfau Civil Hospital, Karachi, Sindh, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i4.1115

Keywords:

Preterm Birth, Labor Ward, Adverse Pregnancy Outcomes, Risk Factors

Abstract

Background: Preterm birth remains a widespread issue worldwide, ranking as a leading cause of neonatal mortality and a significant contributor to long-term health complications. Its multifactorial nature, involving both individual and environmental influences, poses challenges for effective prediction and prevention during antenatal care. While the global incidence of preterm births continues to rise, there is a notable lack of comprehensive data from developing nations like Pakistan. Methods: This cross-sectional study was conducted at Dr. Ruth K.M. Pfau Civil Hospital, Karachi, over six months (from July 01, 2024 to December 31, 2024), to determine the frequency and associated factors of preterm labor. A total of 213 women aged 18–45 years undergoing delivery were included using non-probability consecutive sampling. Data on demographics, clinical details, and BMI, categorized using Asian criteria, were collected. Preterm labor was diagnosed based on uterine contractions and cervical assessment. Data were analyzed using SPSS version 21, with stratification and chi-square/Fisher’s exact test applied to control effect modifiers. A p-value ≤ 0.05 was considered significant. Results provided insights into the prevalence and risk factors of preterm labor. Results: Among 213 participants, 26.29% experienced preterm labor with most preterm babies fell within the mild category (32–36 weeks, 60.7%) while moderate preterm (28–31 weeks, 26.8%) cases were second with extreme preterm (24–27 weeks, 12.5%) coming in as the least common. Chi-square tests revealed no significant relationships with residence, parity, or previous C-sections. Independent t-tests found no significant differences in continuous variables between groups. However, previous preterm delivery significantly predicted current preterm labor (p = 0.04). These findings suggest that preterm labor may be influenced by unmeasured or complex factors. Conclusion: This study found that previous preterm delivery was the only significant predictor of preterm labor, while factors such as age, BMI, residence, parity, and previous C-section showed no meaningful associations. These results emphasize the importance of focused interventions for women with a history of preterm birth to improve pregnancy outcomes.

Downloads

Download data is not yet available.

References

World Health Organization. (2004). ICD-10: International statistical classification of diseases and related health problems, 10th revision. Volume 2. 2nd ed. Geneva: WHO.

Taylor M. (2010). Preterm labor. In Obstetric and Gynaecology. An evidence based text for MRCOG. 2nd edition. https://doi.org/10.1201/b13306-51

Andrews, J. C., & Lawson, H. W. (2016). The role of the male in preventing HPV-related diseases. Journal of Lower Genital Tract Disease, 20(3), 195-196. https://doi.org/10.1097/lgt.0000000000000226

Turab, A., Pell, L. G., Bassani, D. G., Soofi, S., Ariff, S., Bhutta, Z. A., & Morris, S. K. (2014). The community-based delivery of an innovative neonatal kit to save newborn lives in rural Pakistan: Design of a cluster randomized trial. BMC Pregnancy and Childbirth, 14(1). https://doi.org/10.1186/1471-2393-14-315

Blencowe, H., Cousens, S., Oestergaard, M. Z., Chou, D., Moller, A., Narwal, R., Adler, A., Vera Garcia, C., Rohde, S., Say, L., & Lawn, J. E. (2012). National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: A systematic analysis and implications. The Lancet, 379(9832), 2162-2172. https://doi.org/10.1016/s0140-6736(12)60820-4

CLARK, E. A., & VARNER, M. (2011). Impact of preterm PROM and its complications on long-term infant outcomes. Clinical Obstetrics & Gynecology, 54(2), 358-369. https://doi.org/10.1097/grf.0b013e318217ee18

Svigos, J. M., Dodd, J. M., & Robinson, J. S. (2011). Threatened and actual preterm labor including mode of delivery. High Risk Pregnancy, 1075-1090.e4. https://doi.org/10.1016/b978-1-4160-5908-0.00061-2

Born-to-soon-the-global-action-report-on-preterm-birth. (2012). Human Rights Documents online. https://doi.org/10.1163/2210-7975_hrd-9831-0027

Crowther, C. A., & Han, S. (2010). Hospitalisation and bed rest for multiple pregnancy. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.cd000110.pub2

Azher, T., Aslam, I., Bano, S., & Shahzad, U. (2017). Preterm labour:. The Professional Medical Journal, 24(09), 1376-1379. https://doi.org/10.29309/tpmj/2017.24.09.811

Rukhsana FK, Ramzan S, Kamal R, Khan R. (2022). Frequency of preterm labour in women presenting with short interpregnancy interval. Pakistan Journal of Medical and Health Sciences, 16(6), 96-97. https://doi.org/10.53350/pjmhs2216696

Hanif, A., Ashraf, T., Pervaiz, M., & Guler, N. (2020). Prevalence and risk factors of preterm birth in Pakistan. Journal of the Pakistan Medical Association, 70(4), 577-582. https://doi.org/10.5455/jpma.295022

Fatima, M., Naz, U., Hira, A. K., Habib, A., Kazi, P. S., & Majeed, H. (2021). Association between pre-term labour and inter pregnancy interval. Pakistan Journal of Medical and Health Sciences, 15(10), 3137-3139. https://doi.org/10.53350/pjmhs2115103137

Slattery, M. M., & Morrison, J. J. (2002). Preterm delivery. The Lancet, 360(9344), 1489-1497. https://doi.org/10.1016/s0140-6736(02)11476-0

Dekker, G. A., Lee, S. Y., North, R. A., McCowan, L. M., Simpson, N. A., & Roberts, C. T. (2012). Risk factors for preterm birth in an international prospective cohort of nulliparous women. PLoS ONE, 7(7), e39154. https://doi.org/10.1371/journal.pone.0039154

Najafi, Z., Mirghafourvand, M., & Ghanbari-Homaie, S. (2023). Are women with preterm labour at risk for negative birth experience? a comparative cross-sectional study from Iran. BMC Pregnancy and Childbirth, 23(1). https://doi.org/10.1186/s12884-023-05575-9

Breuking, S. H., De Ruigh, A. A., Hermans, F. J., Schuit, E., Combs, C. A., De Tejada, B. M., Oudijk, M. A., Mol, B. W., & Pajkrt, E. (2023). Progestogen maintenance therapy for prolongation of pregnancy after an episode of preterm labour: A systematic review and meta‐analysis. BJOG: An International Journal of Obstetrics & Gynaecology, 130(11), 1306-1316. https://doi.org/10.1111/1471-0528.17499

Makhijani, P., Kazi, S., & Rabia, S. (2017). Factors associated with the failed induction of labour in post-term pregnancy at a tertiary care hospital in Karachi, Pakistan. Journal of the Dow University of Health Sciences, 11(3), 67-71. https://doi.org/10.36570/jduhs.2017.3.524

Hagen, C. A. (1995). Maternal mortality, fertility, and the utilization of prenatal care in Karachi, Pakistan. https://escholarship.mcgill.ca/concern/theses/j6731608q

Ali, S. M., Karamat, S., Jabbar Khawaja, A. A., Urooj, H., Shaikh, F., Farooq, S., & Zeba, N. (2020). Frequency of maternal and neonatal complications associated with second stage caesarean section in civil hospital Karachi, Pakistan. The Professional Medical Journal, 27(03), 535-539. https://doi.org/10.29309/tpmj/2020.27.03.3429

Anumba, D. O. (2007). Management of women with a previous preterm birth. Obstetrics, Gynaecology & Reproductive Medicine, 17(6), 188-191. https://doi.org/10.1016/j.ogrm.2007.04.001

Downloads

Published

2025-04-26

How to Cite

Frequency of Preterm Labour in Women Attending Delivery Suite of Civil Hospital, Karachi. (2025). Indus Journal of Bioscience Research, 3(4), 559-564. https://doi.org/10.70749/ijbr.v3i4.1115