Prevalence of Portopulmonary Hypertension in Patients with Hepatic Cirrhosis

Authors

  • Umar Javaid Sandhu Department of Medicine, Ghurki Trust Teaching Hospital, Lahore, Punjab, Pakistan.
  • Ayesha Chaudhary Department of Medicine, Allied Hospital, Faisalabad, Punjab, Pakistan.
  • Ahmad Salman Jami Department of Medicine, Ghurki Trust Teaching Hospital, Lahore, Punjab, Pakistan.
  • Hafiz Bilal Wajid Department of Medicine, Ghurki Trust Teaching Hospital, Lahore, Punjab, Pakistan.
  • Farah Shakeel Department of Medicine, Ghurki Trust Teaching Hospital, Lahore, Punjab, Pakistan.
  • Gull Seira Department of Medicine, Ghurki Trust Teaching Hospital, Lahore, Punjab, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i7.1674

Keywords:

Portopulmonary Hypertension, Hepatic Cirrhosis

Abstract

Objective: “To determine the frequency of portopulmonary hypertension in patients with hepatic cirrhosis.” Study Place and Duration: Department of Medicine, Ghurki Trust Teaching Hospital, Lahore for 05 months from 7th Feb 2025 to 8th June 2025. Methodology: After meeting the selection criteria, 130 patients were and underwent portal vein Doppler ultrasound and echocardiography. Portopulmonary hypertension was diagnosed if the patient had a tricuspid regurgitation velocity ≥2.8 m/s, an estimated pulmonary artery systolic pressure >35 mmHg on echocardiography, pulmonary arterial pressure >20 mmHg, pulmonary artery wedge pressure ≤15 mmHg, and pulmonary vascular resistance ≥3 Wood units. All findings were documented in a structured proforma and analysed in SPSS. Results: The mean age of participants was 55.40  ±  9.76 years. Among them, 71 (54.6%) were male and 59 (45.4%) were female. In this study, porto-pulmonary hypertension was observed in 14 patients (10.77%) with hepatic cirrhosis. Among males, 4 (5.6%) had portopulmonary hypertension, compared to 10 (16.9%) females (p = 0.038*). Conclusion: Based on the findings of this study, it can be concluded that portopulmonary hypertension was present in 10.77% of patients with hepatic cirrhosis, with a higher prevalence observed among females.

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References

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Published

2025-07-14

How to Cite

Umar Javaid Sandhu, Ayesha Chaudhary, Ahmad Salman Jami, Hafiz Bilal Wajid, Farah Shakeel, & Gull Seira. (2025). Prevalence of Portopulmonary Hypertension in Patients with Hepatic Cirrhosis. Indus Journal of Bioscience Research, 3(7), 128-132. https://doi.org/10.70749/ijbr.v3i7.1674