Frequency of Prediabetes in Acute Stroke Patients Presenting at Tertiary Care Hospital, Karachi

Authors

  • Guriya Department of Medicine, Ward 6, Jinnah Postgraduate Medical Center, Karachi, Pakistan
  • Rukshanda Jabeen Department of Medicine, Ward 6, Jinnah Postgraduate Medical Center, Karachi, Pakistan
  • Soniya Department of Medicine, Ward 6, Jinnah Postgraduate Medical Center, Karachi, Pakistan
  • Ayesha Ejaz Department of Medicine, Ward 6, Jinnah Postgraduate Medical Center, Karachi, Pakistan
  • Lubna Gul Department of Medicine, Ward 6, Jinnah Postgraduate Medical Center, Karachi, Pakistan
  • Aakash Kumar Department of Medicine, UMDC, Karachi, Pakistan

DOI:

https://doi.org/10.70749/ijbr.v3i7.1832

Keywords:

Prediabetes, acute stroke, ischemic stroke, dysglycemia, risk factors, tertiary care, Karachi

Abstract

Background: Prediabetes, an intermediate state of abnormal glucose metabolism, is increasingly recognized as a risk factor for cardiovascular disease, including stroke. However, limited local data exist on its prevalence among acute stroke patients in Pakistan. Objective: To determine the frequency of prediabetes in patients presenting with acute stroke at a tertiary care hospital in Karachi. Methods: This cross-sectional study was conducted at a tertiary care hospital in Karachi. A total of 189 patients admitted with a diagnosis of acute stroke were included. Demographic data, clinical history, and laboratory findings were recorded. Prediabetes was defined random blood sugar 100 to 125 mg/dL. Data were analyzed using descriptive statistics and chi-square tests to identify associations between prediabetes and baseline variables. Results: Out of 189 patients, 53 (28%) were identified with prediabetes. Prediabetes was more frequent in the 40–60 years age group (43.1%) compared to older patients (20.2%) (p = 0.01). No significant association was found between prediabetes and gender (p = 0.29) or hypertension (p = 0.17). However, a statistically significant association was observed between prediabetes and dyslipidemia (p = 0.01). Smoking status also showed a marginal association with prediabetes (p = 0.05). Conclusion: A considerable proportion of acute stroke patients had prediabetes, particularly among middle-aged individuals. Routine screening for prediabetes in stroke patients may help identify at-risk individuals early and enable timely interventions to prevent diabetes and recurrent vascular events.

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Published

2025-07-15

How to Cite

Guriya, Jabeen, R., Soniya, Ejaz, A., Gul, L., & Kumar, A. (2025). Frequency of Prediabetes in Acute Stroke Patients Presenting at Tertiary Care Hospital, Karachi. Indus Journal of Bioscience Research, 3(7), 435-439. https://doi.org/10.70749/ijbr.v3i7.1832