Diagnostic Accuracy of Ultrasonography in Diagnosis of Acute Appendicitis in Pediatric Population

Authors

  • Fizza Aman Diagnostic Radiology Department, Bolan Medical College Hospital (BMCH), Quetta, Balochistan, Pakistan.
  • Rizwana Rehman Diagnostic Radiology Department, Bolan Medical College Hospital (BMCH), Quetta, Balochistan, Pakistan.
  • Sabahat Gul Diagnostic Radiology Department, Bolan Medical College Hospital (BMCH), Quetta, Balochistan, Pakistan.
  • Mahrukh Panezai Diagnostic Radiology Department, Bolan Medical College Hospital (BMCH), Quetta, Balochistan, Pakistan.
  • Summaya Bashir Diagnostic Radiology Department, Bolan Medical College Hospital (BMCH), Quetta, Balochistan, Pakistan.
  • Rehanna Sarwar Diagnostic Radiology Department, Bolan Medical College Hospital (BMCH), Quetta, Balochistan, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i7.1982

Keywords:

Ultrasonography, Acute Appendicitis, Pediatric Diagnosis

Abstract

Background: One of the most frequent reasons why children require emergency abdominal surgery is acute appendicitis. In order to avoid problems including perforation, abscess formation, and needless surgery, an accurate and prompt diagnosis is essential. Because it is non-invasive and radiation-free, ultrasound (USG) is commonly utilized as a first imaging modality, particularly for young patients. Objective: The purpose of this study was to compare sonographic findings with intraoperative and histological data in order to assess the diagnostic accuracy of ultrasonography in identifying acute appendicitis in the pediatric population. Methodology: Over the course of six months, a qualitative study was carried out in a tertiary care hospital's emergency room from November 2024 to May 2025. Ultrasonography was performed on 130 children, ages 5 to 18, who had a clinical suspicion of appendicitis. To evaluate sensitivity, specificity, and predictive qualities, USG results were contrasted with surgical and histological results. Results: The results showed that ultrasonography had a 90.2% sensitivity, 57.1% specificity, 88.5% positive predictive value, and 61.5% negative predictive value. Non-compressible tubular structure >6 mm (75.4%) and wall thickening (70.8%) were common sonographic findings. 102 cases (78.5%) had appendicitis confirmed by final diagnosis; the stages included suppurative, gangrenous, and perforated types. Conclusion: Ultrasonography is a safe, dependable, and reasonably priced method for identifying children's acute appendicitis early on. Even if it depends on the operator, it is essential for directing clinical judgements and minimizing needless procedures, especially in environments with limited resources.

Downloads

Download data is not yet available.

References

1. Pinto, F., Pinto, A., Russo, A., Coppolino, F., Bracale, R., Fonio, P., Macarini, L., & Giganti, M. (2013). Accuracy of ultrasonography in the diagnosis of acute appendicitis in adult patients: Review of the literature. Critical Ultrasound Journal, 5(S1).

https://doi.org/10.1186/2036-7902-5-s1-s2

2. Bhangu, A., Søreide, K., Di Saverio, S., Assarsson, J. H., & Drake, F. T. (2015). Acute appendicitis: Modern understanding of pathogenesis, diagnosis, and management. The Lancet, 386(10000), 1278-1287.

https://doi.org/10.1016/s0140-6736(15)00275-5

3. Yildiz, T., Ilce, Z., Turan, G., Bozdag, Z., & Elmas, B. (2015). Parasites in the etiology of pediatric appendicitis. Turkish Journal of Parasitology, 39(3), 190-193.

https://doi.org/10.5152/tpd.2015.3737

4. Öztaş, T., Dursun, A., Söğütçü, N., & Bilici, S. (2018). Unusual histopathological findings in appendectomy specimens obtained from 1683 pediatric patients with suspected acute appendicitis. Indian Journal of Surgery, 81(4), 344-349.

https://doi.org/10.1007/s12262-018-1814-4

5. Okoro, K. U., De La Espriella, M. G., Grider, D. J., & Baffoe-Bonnie, A. W. (2018). Tuberculous enteritis presenting as acute appendicitis and Perirectal abscess. Case Reports in Medicine, 2018, 1-5.

https://doi.org/10.1155/2018/6068258

6. Almaramhy, H. H. (2017). Acute appendicitis in young children less than 5 years: Review article. Italian Journal of Pediatrics, 43(1).

https://doi.org/10.1186/s13052-017-0335-2

7. Short, H. L., Sarda, S., Travers, C., Hockenberry, J. M., McCarthy, I., & Raval, M. V. (2018). Trends in common surgical procedures at children’s and nonchildren’s hospitals between 2000 and 2009. Journal of Pediatric Surgery, 53(8), 1472-1477.

https://doi.org/10.1016/j.jpedsurg.2017.11.053

8. Blitman, N. M., Anwar, M., Brady, K. B., Taragin, B. H., & Freeman, K. (2015). Value of focused appendicitis ultrasound and Alvarado score in predicting appendicitis in children: Can we reduce the use of CT? American Journal of Roentgenology, 204(6), W707-W712.

https://doi.org/10.2214/ajr.14.13212

9. Dilley, A., Wesson, D., Munden, M., Hicks, J., Brandt, M., Minifee, P., & Nuchtern, J. (2001). The impact of ultrasound examinations on the management of children with suspected appendicitis: A 3-year analysis. Journal of Pediatric Surgery, 36(2), 303-308.

https://doi.org/10.1053/jpsu.2001.20702

10. Kaiser, S., Jorulf, H., Söderman, E., & Frenckner, B. (2004). Impact of radiologic imaging on the surgical decision-making process in suspected appendicitis in children1. Academic Radiology, 11(9), 971-979.

https://doi.org/10.1016/j.acra.2004.05.023

11. Bachur, R. G., Dayan, P. S., Bajaj, L., Macias, C. G., Mittal, M. K., Stevenson, M. D., Dudley, N. C., Sinclair, K., Bennett, J., Monuteaux, M. C., & Kharbanda, A. B. (2012). The effect of abdominal pain duration on the accuracy of diagnostic imaging for pediatric appendicitis. Annals of Emergency Medicine, 60(5), 582-590.e3.

https://doi.org/10.1016/j.annemergmed.2012.05.034

12. Erikci, V. S. (2018). Management of pediatric appendicitis. Current Issues in the Diagnostics and Treatment of Acute Appendicitis.

https://doi.org/10.5772/intechopen.72793

13. Alvarado, A. (2018). Clinical approach in the diagnosis of acute appendicitis. Current Issues in the Diagnostics and Treatment of Acute Appendicitis.

https://doi.org/10.5772/intechopen.75530

14. Nielsen, J. W., Boomer, L., Kurtovic, K., Lee, E., Kupzyk, K., Mallory, R., Adler, B., Bates, D. G., & Kenney, B. (2015). Reducing computed tomography scans for appendicitis by introduction of a standardized and validated ultrasonography report template. Journal of Pediatric Surgery, 50(1), 144-148.

https://doi.org/10.1016/j.jpedsurg.2014.10.033

15. Sauvain, M., Slankamenac, K., Muller, M. K., Wildi, S., Metzger, U., Schmid, W., Wydler, J., Clavien, P., & Hahnloser, D. (2016). Delaying surgery to perform CT scans for suspected appendicitis decreases the rate of negative appendectomies without increasing the rate of perforation nor postoperative complications. Langenbeck's Archives of Surgery, 401(5), 643-649.

https://doi.org/10.1007/s00423-016-1444-x

16. Boonstra, P. A., Van Veen, R. N., & Stockmann, H. B. (2014). Less negative appendectomies due to imaging in patients with suspected appendicitis. Surgical Endoscopy, 29(8), 2365-2370.

https://doi.org/10.1007/s00464-014-3963-2

17. Kessler, N., Cyteval, C., Gallix, B., Lesnik, A., Blayac, P., Pujol, J., Bruel, J., & Taourel, P. (2004). Appendicitis: Evaluation of sensitivity, specificity, and predictive values of US, Doppler US, and laboratory findings. Radiology, 230(2), 472-478.

https://doi.org/10.1148/radiol.2302021520

18. Flum, D. R., Morris, A., Koepsell, T., & Dellinger, E. P. (2001). Has misdiagnosis of appendicitis decreased over time? JAMA, 286(14), 1748.

https://doi.org/10.1001/jama.286.14.1748

19. Sauerland, S., Lefering, R., & Neugebauer, E. A. (2004). Laparoscopic versus open surgery for suspected appendicitis. Cochrane Database of Systematic Reviews.

https://doi.org/10.1002/14651858.cd001546.pub2

20. Guller, U., Hervey, S., Purves, H., Muhlbaier, L. H., Peterson, E. D., Eubanks, S., & Pietrobon, R. (2004). Laparoscopic versus open appendectomy. Annals of Surgery, 239(1), 43-52.

https://doi.org/10.1097/01.sla.0000103071.35986.c1

21. Blomqvist, P. G., Andersson, R. E., Granath, F., Lambe, M. P., & Ekbom, A. R. (2001). Mortality after appendectomy in Sweden, 1987–1996. Annals of Surgery, 233(4), 455-460.

https://doi.org/10.1097/00000658-200104000-00001

22. Vinz, H., & Neu, J. (2007). Malpractice claims relating to the diagnosis and treatment of acute appendicitis--decisions of the Norddeutsche Schlichtungsstelle (Expert Panel for Extrajudicial Claims Resolution of the Medical Associations in Northern Germany). Zeitschrift fur Arztliche Fortbildung und Qualitatssicherung, 101(8), 553-563.

https://doi.org/10.1016/j.zgesun.2007.08.034

23. Benabbas, R., Hanna, M., Shah, J., & Sinert, R. (2017). Diagnostic accuracy of history, physical examination, laboratory tests, and point‐of‐care ultrasound for pediatric acute appendicitis in the emergency department: A systematic review and meta‐analysis. Academic Emergency Medicine, 24(5), 523-551.

https://doi.org/10.1111/acem.13181

24. Doria, A. S., Moineddin, R., Kellenberger, C. J., Epelman, M., Beyene, J., Schuh, S., Babyn, P. S., & Dick, P. T. (2006). US or CT for diagnosis of appendicitis in children and adults? A meta-analysis. Radiology, 241(1), 83-94.

https://doi.org/10.1148/radiol.2411050913

25. Trout, A. T., Sanchez, R., Ladino-Torres, M. F., Pai, D. R., & Strouse, P. J. (2012). A critical evaluation of US for the diagnosis of pediatric acute appendicitis in a real-life setting: how can we improve the diagnostic value of sonography? Pediatric Radiology, 42(7), 813–823.

https://doi.org/10.1007/s00247-012-2358-6

26. Garcia Peña, B. M., Taylor, G. A., Fishman, S. J., Mandl, K. D. (2016). Effects of an Imaging Protocol on Clinical Outcomes Among Pediatric Patients With Appendicitis. Pediatrics, 138(1), e20154340.

https://doi.org/10.1542/peds.2015-4340

Downloads

Published

2025-07-15

How to Cite

Aman, F., Rehman, R., Gul, S., Panezai, M., Bashir, S., & Sarwar, R. (2025). Diagnostic Accuracy of Ultrasonography in Diagnosis of Acute Appendicitis in Pediatric Population. Indus Journal of Bioscience Research, 3(7), 516-520. https://doi.org/10.70749/ijbr.v3i7.1982