Frequency of Acute Pancreatitis in Patient Presenting With Acute Abdomen
DOI:
https://doi.org/10.70749/ijbr.v3i7.2220Keywords:
Acute abdomen, acute pancreatitis, hypertension, diabetes mellitus.Abstract
Background: Acute abdomen pain, a nontraumatic abdominal pain of shorter than seven days' duration, is a frequent presenting complaint with broad differential diagnosis. Acute pancreatitis (AP) is an extremely frequent GI disease and the incidence of AP has risen over the last decade across the world. Gallstone Alcohol and hypertriglyceridemia are the most common causes of AP. Objective: To figure out the frequency of acute pancreatitis among patients with acute abdomen. Methodology: The study was cross-sectional and was carried out in surgical department of Ayub Teaching Hospital, Abbottabad. 121 patients were seen coming with acute abdomen for the duration from January 2025 to May 2025. Non-probability consecutive specimen was used for sampling. Results: The study's participants ranged in age from 18 to 60, with a mean age of 37.2 ± 6.2 years, mean complaint duration of 1.26 ±0.52, and mean BMI was 24.4 ±3.4. Frequency of acute pancreatitis was 11(9.1%) out of total 121 patients of acute abdomen, diabetes mellitus in 22(18.2%) and hypertension in 46(38%) patients. On data stratification there was statistically significant Diabetes mellitus and acute pancreatitis are related. As clear from table no-3. There was no association between acute pancreatitis and hypertension, gender and patient's BMI. Conclusion: This study suggests that nearly one in ten patients presenting with acute abdomen may have acute pancreatitis and the diabetic patients are at increased risk than normal population. The emergency surgeon evaluating acute abdominal pain should maintain high suspicion for pancreatitis in individuals with diabetes. Early recognition, targeted biochemical and imaging investigations in these individuals may facilitate in prompt diagnosis, appropriate management, and reduction of morbidity/mortality
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References
1. Yew KS, George MK, Allred HB. Acute abdominal pain in adults: evaluation and diagnosis. Am Fam Physician. 2023;107(6):585-96.
2. Elhardello OA, MacFie J. Digital rectal examination in patients with acute abdominal pain. Emerg Med J. 2018;35(9):579-80.
https://doi.org/10.1136/emermed-2018-207631
3. Maleki-Verki M, Motamed H. Rectus muscle hematoma as a rare differential diagnosis of acute abdomen; a case report. Emerg. 2018;6(1):e28-32.
4. Kaushal-Deep SM, Anees A, Khan S, Khan MA, Lodhi M. Primary cecal pathologies presenting as acute abdomen and critical appraisal of their current management strategies in emergency settings with review of literature. Int J Crit Illn Inj Sci. 2018;8(2):90-9.
https://doi.org/10.4103/ijciis.ijciis_69_17
5. Geng WZM, Fuller M, Osborne B, Thoirs K. The value of the erect abdominal radiograph for the diagnosis of mechanical bowel obstruction and paralytic ileus in adults presenting with acute abdominal pain. J Med Radiat Sci. 2018;65(4):259-66.
https://doi.org/10.1002/jmrs.299
6. Mohammed MF, Elbanna KY, Mohammed AME, Murray N, Azzumea F, Almazied G, et al. Practical applications of dual-energy computed tomography in the acute abdomen. Radiol Clin North Am. 2018;56(4):549-63.
https://doi.org/10.1016/j.rcl.2018.03.004
7. Hong W, Zimmer V, Basharat Z, Zippi M, Stock S, Geng W, et al. Association of total cholesterol with severe acute pancreatitis: a U-shaped relationship. Clin Nutr. 2020;39:250–7.
https://doi.org/10.1016/j.clnu.2019.01.022
8. Lee PJ, Papachristou GI. New insights into acute pancreatitis. Nat Rev Gastroenterol Hepatol. 2019;16:479–96.
https://doi.org/10.1038/s41575-019-0158-2
9. He W, Wang G, Yu B, Xia L, Zhu Y, Liu P, et al. Elevated hypertriglyceridemia and decreased gallstones in the etiological composition ratio of acute pancreatitis as affected by seasons and festivals: a two-center real-world study from China. Front Cell Infect Microbiol. 2022;12:976816-9.
https://doi.org/10.3389/fcimb.2022.976816
10. Abdullah MT, Hanif A, Waqar SH, Shah SF, Malik ZI, Zahid MA. Presentation and outcome of acute abdomen in a tertiary care unit. Ann Pak Inst Med Sci. 2011;7(3):137-41.
11. Wang GJ, Gao CF, Wei D, Wang C, Ding SQ. Acute pancreatitis: etiology and common pathogenesis. World journal of gastroenterology: WJG. 2009 Mar 28;15(12):1427.
https://doi.org/10.3748/wjg.15.1427
12. Zahid M, Abdullah MT, PIMS I. Presentation and outcome of acute abdomen in a tertiary care unit. Ann Pak Inst Med Sci. 2011;7(3):137-41.
13. Richardson A, Park WG. Acute pancreatitis and diabetes mellitus: a review. The Korean journal of internal medicine. 2020 Dec 4;36(1):15.
https://doi.org/10.3904/kjim.2020.505
14. Yadav D, Lowenfels AB. The epidemiology of pancreatitis and pancreatic cancer. Gastroenterology. 2013 May 1;144(6):1252-61.
https://doi.org/10.1053/j.gastro.2013.01.068
15. Shen HN, Chang YH, Chen HF, Lu CL, Li CY. Increased risk of severe acute pancreatitis in patients with diabetes. Diabetic medicine. 2012 Nov;29(11):1419-24.
https://doi.org/10.1111/j.1464-5491.2012.03680.x
16. Potts JR 3rd. Acute pancreatitis. Surg Clin North Am. 1988 Apr;68(2):281-99. PMID: 3279547.
https://doi.org/10.1016/s0039-6109(16)44478-6.
17. Eland IA, Sundström A, Velo GP, Andersen M, Sturkenboom MC, Langman MJ, Stricker BH, Wiholm B, Eland IA, Sundström A, Velo GP. Antihypertensive medication and the risk of acute pancreatitis: the European case-control study on drug-induced acute pancreatitis (EDIP). Scandinavian journal of gastroenterology. 2006 Jan 1;41(12):1484-90.
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