Frequency of Intraoperative Complications in Patients Undergoing Laparoscopic Cholecystectomy
DOI:
https://doi.org/10.70749/ijbr.v3i7.2323Keywords:
Cholecystectomy, Morbidity, Laparoscopy, Liver, Surgical procedures, Operative.Abstract
Background: Laparoscopic cholecystectomy is the standard treatment for gallstone disease, offering advantages such as reduced postoperative pain, shorter hospital stays, and faster recovery. Despite being considered safe, intraoperative complications such as liver bed injury, bleeding from Calot’s triangle, trocar site bleeding, and bile leakage can occur and may influence surgical outcomes. Limited regional data exist regarding the frequency and risk factors of these complications in Peshawar. Objective: To find out the frequency of intra operative complication in patients undergoing laparoscopic cholecystectomy. Study Design: Descriptive observational study. Duration and Place of Study: The study was conducted in the Department of General Surgery, Lady Reading Hospital, Peshawar, from December 2024 to May 2025. Methodology: A total of 236 patients aged 18–65 years undergoing laparoscopic cholecystectomy were included through consecutive non-probability sampling. Patients with obstructive jaundice, gallbladder malignancy, or pregnancy were excluded. Complications were documented intraoperatively as liver bed injury, bleeding from Calot’s triangle, trocar site bleeding, or bile leakage. Results: Among 236 patients (mean age 41.18±13.86 years, 66.5% female), the frequencies of complications were: liver bed injury 8.1%, bleeding from Calot’s triangle 4.7%, trocar site bleeding 8.1%, and bile leakage 7.2%. Significant associations were found between liver bed injury and age ≤45 years (p=0.030), bile leakage and female gender (p=0.049), bleeding complications and BMI >25 kg/m² (p=0.008, p=0.006), and higher rates of liver bed injury and Calot’s bleeding in rural patients (p=0.015, p=0.026). Conclusion: Intraoperative complications during laparoscopic cholecystectomy occur with acceptable frequencies but are significantly influenced by age, gender, BMI, and place of residence, emphasizing the importance of careful preoperative assessment and surgical precision.
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References
1. Toppo S, Gaurav K, Kumar K, Kumar K, Verma S, Tudoo ST, et al. Assessment of predictors of difficult laparoscopic cholecystectomy by clinico-radiological parameters at a tertiary hospital in eastern India. Cureus. 2024;16(10):e72512.
https://doi.org/10.7759/cureus.72512
2. Nafea MA, Elshafey MH, Hegab A, Seleem A, Rafat W, Khairy M, et al. Open versus laparoscopic completion cholecystectomy in patients with previous open partial cholecystectomy: a retrospective comparative study. Ann Med Surg (Lond). 2024;86(10):5688-5695.
https://doi.org/10.1097/MS9.0000000000002428
3. Ravendran K, Elmoraly A, Kagiosi E, Henry CS, Joseph JM, Kam C. Converting from laparoscopic cholecystectomy to open cholecystectomy: a systematic review of its advantages and reasoning. Cureus. 2024;16(7):e64694.
https://doi.org/10.7759/cureus.64694
4. Pesce A, Fabbri N, Feo CV. Vascular injury during laparoscopic cholecystectomy: an often-overlooked complication. World J Gastrointest Surg. 2023;15(3):338-345.
https://doi.org/10.4240/wjgs.v15.i3.338
5. Korayem IM, Bessa SS. Preoperative predictors of difficult early laparoscopic cholecystectomy among patients with acute calculous cholecystitis in Egypt. BMC Surg. 2024;24(1):329.
https://doi.org/10.1186/s12893-024-02532-x
6. Haidar MGM, Sharaf NAH, Saleh SA, Upadhyay P. Rare anatomical variants encountered during laparoscopic cholecystectomy in low resource conditions and the convenient concept of the safe zone of dissection: a prospective observational study at a single center. J Minim Invasive Surg. 2024;27(3):156-164.
https://doi.org/10.7602/jmis.2024.27.3.156
7. Renz BW, Bösch F, Angele MK. Bile duct injury after cholecystectomy: surgical therapy. Visc Med. 2017;33(3):184-190.
https://doi.org/10.1159/000471818
8. Radunovic M, Lazovic R, Popovic N, Magdelinic M, Bulajic M, Radunovic L, et al. Complications of laparoscopic cholecystectomy: our experience from a retrospective analysis. Open Access Maced J Med Sci. 2016;4(4):641-646.
https://doi.org/10.3889/oamjms.2016.128
9. Jindal A, Badu NYA, Katiki C, Ponnapalli VJS, Desai KJ, Mansoor S, et al. Factors influencing bile duct injuries: a dreaded complication of laparoscopic cholecystectomy. Cureus. 2024;16(11):e73600.
https://doi.org/10.7759/cureus.73600
10. Yang JP, Tian Z. Analysis of the effect of laparoscopic cholecystectomy for acute cholecystitis after percutaneous transhepatic gallbladder puncture and drainage. Evid Based Complement Alternat Med. 2022;2022:2071326.
https://doi.org/10.1155/2022/2071326
11. Agarwal S, Joshi AD. Perioperative complications of laparoscopic cholecystectomy: a cross-sectional observational study. Int Surg J. 2020;7(5):1490-1495.
https://doi.org/10.18203/2349-2902.isj20201857
12. Bharai SK, Sindhal M. Perioperative challenges in laparoscopic cholecystectomy: a comprehensive review. Int J Pharm Clin Res. 2024;16(3):731-736.
13. Rahman A, Rahman M, Uddin MS, Taher A, Masum MG. A retrospective study among patients undergoing laparoscopic cholecystectomy: intraoperative and postoperative complications. Int Surg J. 2023;10(1):18-22.
https://doi.org/10.18203/2349-2902.isj2022547
14. Muqim R, Jan QA, Zarin M, Aurangzaib M, Wazir A. Complications of laparoscopic cholecystectomy. World J Lap Surg. 2008;1(1):1-5.
https://doi.org/10.5005/jp-journals-10007-1039
15. Suthar KR, Vyas PH, Patel NJ, Parikh SG, Solanki GK. Evaluative study of outcome of patients undergoing laparoscopic cholecystectomy. World J Lap Surg. 2023;16(2):84-87.
https://doi.org/10.1155/2023/7838103
16. Waqar SH, Abdullah MT, Shah SA, Malik ZI, Shahzad F. Outcome of laparoscopic cholecystectomy in patients of acute cholecystitis. JIIMC. 2020;15(3):149-153.
17. Iftikhar M, Qazi MS, Khan R, Ahmad S, Ullah S, Ullah F. Comparative analysis of complications in early versus delayed laparoscopic cholecystectomy for acute cholecystitis. Cureus. 2025;17(2):e78985.
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