Frequency of Grades of Oral Squamous Cell Carcinoma in Male Tobacco Smokers

Sohail Mahmood Ahmad; Samreen Hameed

doi:10.70749/ijbr.v3i5.2428

Authors

Sohail Mahmood Ahmad Department of Pathology (Histopathology), King Edward Medical University, Lahore, Pakistan
Samreen Hameed Department of Pathology (Histopathology), King Edward Medical University, Lahore, Pakistan

DOI:

https://doi.org/10.70749/ijbr.v3i5.2428

Keywords:

Tobacco smokers, male, oral squamous cell carcinoma, grades

Abstract

Background: Tobacco has over 60 harmful compounds that may enter the body and cause damage. Around 90% of all cases of oral cancer are diagnosed as oral squamous cell carcinoma (OSCC). Tobacco's carcinogenic routes may be complex, as shown by the large body of scientific, clinical, and epidemiological research linking tobacco use to the onset of oral squamous cell carcinoma. Study Design and Settings: It was a descriptive cross-sectional study. The study was conducted in the Pathology Department of King Edward Medical University with collaboration of Oncology, Maxillofacial, and Surgical Departments of Mayo Hospital Lahore. Duration of Study: The study was conducted six months after approval of the synopsis, from 16^th August 2022 to 15^th February 2023. METHODOLOGY: It was a descriptive cross-sectional study. Seventy-four patients presenting to oral maxillofacial and surgical departments with oral lesions were biopsied. All biopsies were sent to the Pathology Department of KEMU for processing and reporting. Patients' demographics, duration and frequency of tobacco smoking, histological diagnosis, and grade were noted in a predesigned proforma after taking informed consent. RESULTS: In our study, the mean age of patients was 45.57±9.92 years. Duration of smoking was calculated in 63 (85.1%) cases for up to 10 years and 11 (14.9%) had >10 years of smoking. Frequency of grades of oral squamous cell carcinoma in male tobacco smokers shows that 12 (16.2%) cases had grade I, 44 (59.5%) had grade II, and 18 (24.3%) cases had grade III squamous cell carcinoma. CONCLUSION: Frequency of grade II was the commonest grade of oral squamous cell carcinoma in male tobacco smokers in our population.

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