Clinical Applications of Nanotechnology in Drug Delivery for Surgical Patients: Advances in Targeting and Controlled Release
DOI:
https://doi.org/10.70749/ijbr.v3i12.2699Keywords:
Drug Delivery Systems, Nanotechnology, Surgical Patients, Targeted Drug Delivery, Controlled Drug Release, Therapeutic Efficacy, Adverse Effects, Precision MedicineAbstract
This quantitative study examined the clinical applications of nanotechnology-based drug delivery systems in surgical patients, with emphasis on advances in targeted delivery and controlled drug release. A prospective comparative research design was employed in the surgical and perioperative units of a tertiary care hospital, involving a total sample of 120 adult surgical patients selected through consecutive sampling. Participants were divided into two equal groups receiving either nanotechnology-based drug delivery systems or conventional drug formulations. Quantitative data were collected on targeted drug delivery effectiveness, therapeutic outcomes, and adverse effect occurrence. Statistical analyses, including chi-square tests and independent samples t tests, were used to evaluate associations and group differences. The findings revealed that nanotechnology-based drug delivery systems achieved significantly higher rates of effective drug targeting and were associated with reduced adverse drug effects compared to conventional methods (p < .01). Controlled drug release through nanotechnology demonstrated improved therapeutic performance and enhanced drug safety in the postoperative period. These results support the clinical effectiveness of nanotechnology-enabled drug delivery in surgical care and highlight its potential role in advancing precision pharmacotherapy and improving patient outcomes.
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