Frequency of Cesarean Deliveries in Women with Gestational Thrombocytopenia
DOI:
https://doi.org/10.70749/ijbr.v3i7.2796Keywords:
Gestational Thrombocytopenia, Severity, Cesarean Delivery.Abstract
Objectives: To determine the frequency of cesarean deliveries in women with gestational thrombocytopenia. Study type: cross sectional study. Settings: Department of Obs & Gynae, Khan Research Laboratories (KRL) Hospital Islamabad. Duration of study: 25th February 2025 to 24th May 2025. Methodology: Eighty women with singleton pregnancies, no structural abnormalities on obstetrical ultrasound, and gestational thrombocytopenia between the ages of twenty and forty were included. The following conditions were excluded: history of anti-phospholipid anti-body syndrome, immune thrombocytopenia purpura or systemic lupus erythematosus, history of chronic hypertension, diabetes mellitus, liver or renal disease, human immunodeficiency virus infection, hepatitis C infection, or hepatitis B infection; pregnancies complicated by gestational hypertensive disorders, including pre-eclampsia and eclampsia; pregnancies complicated by HELLP (Hemolysis elevated liver enzymes low platelet) syndrome. Every patient underwent obstetrical ultrasonography, which was carried out by a single, skilled CPSP fellow radiologist. One skilled gynecologist, a fellow of the CPSP, performed cesarean deliveries. Results: The study's participants ranged in age from 20 to 40 years, with a mean age of 28.54 ± 5.93 years. Mean gestational age was 33.43 ± 3.52 weeks. Mean platelet count was 123509.43 ± 45638.43/µL. 31 (38.75%) women with gestational thrombocytopenia had undergone cesarean delivery. Conclusion: This study concluded by highlighting the serious fetal problems linked to gestational thrombocytopenia. A tendency toward higher maternal morbidity is indicated by the rising rate of cesarean deliveries.
Downloads
References
1. Park, Y. H. (2022). Diagnosis and management of thrombocytopenia in pregnancy. Blood Research, 57(S1), S79-S85.
https://doi.org/10.5045/br.2022.2022068
2. Hanif, M., Akhtar, T., Ashraf, S., Shahzadi, A., & Rani, H. (2023). Prevalence of Thrombocytopenia in women during third trimester of pregnancy. Pakistan Journal of Medical and Health Sciences, 17(5), 213-215.
https://doi.org/10.53350/pjmhs2023175213
3. Gernsheimer, T., James, A. H., & Stasi, R. (2013). How I treat thrombocytopenia in pregnancy. Blood, 121(1), 38-47.
https://doi.org/10.1182/blood-2012-08-448944
4. Joshi, S. S., & Panchbudhe, S. A. (2022). Characterization of Thrombocytopenia in pregnant women at a tertiary care center: A preliminary study of 121 patients. Journal of South Asian Federation of Obstetrics and Gynaecology, 14(4), 486-490.
https://doi.org/10.5005/jp-journals-10006-2069
5. Reese, J., Peck, J., Deschamps, D., McIntosh, J., Knudtson, E., Terrell, D., Vesely, S., & George, J. (2018). Platelet counts during pregnancy. Obstetric Anesthesia Digest, 38(4), 201-202.
https://doi.org/10.1097/01.aoa.0000547300.10681.29
6. Nair, V. V., Radhamani, M. V., Raju, D. S., & Alphonse, S. C. (2023). CLINICAL PROFILE OF THROMBOCYTOPENIA IN 3RD TRIMESTER OF PREGNANCY AND MATERNAL AND FETAL OUTCOME IN GESTATIONAL THROMBOCYTOPENIA. Int J Acad Med Pharm, 5(1), 762-765.
7. Cines, D. B., & Levine, L. D. (2017). Thrombocytopenia in pregnancy. Blood, 130(21), 2271-2277.
https://doi.org/10.1182/blood-2017-05-781971
8. Pishko, A. M., & Marshall, A. L. (2022). Thrombocytopenia in pregnancy. Hematology, 2022(1), 303-311.
https://doi.org/10.1182/hematology.2022000375
9. Habas, E., Rayani, A., Alfitori, G., Eldin Ahmed, G., & Elzouki, A. Y. (2022). Gestational Thrombocytopenia: A review on recent updates. Cureus.
https://doi.org/10.7759/cureus.23204
10. Fogerty, A. E., & Dzik, W. (2021). Gestational thrombocytopenia: A case–control study of over 3,500 pregnancies. British Journal of Haematology, 194(2), 433-438.
https://doi.org/10.1111/bjh.17611
11. SADULLA, S. M., Y.HMOOD, A., & YOUSIF SHAMDEEN, M. (2020). Gestational thrombocytopenia: Maternal and fetal outcomes in duhok. Duhok Medical Journal, 14(2), 86-96.
https://doi.org/10.31386/dmj.2020.14.2.9
12. Nisha, S., Amita, D., Uma, S., Tripathi, A. K., & Pushplata, S. (2011). Prevalence and characterization of Thrombocytopenia in pregnancy in Indian women. Indian Journal of Hematology and Blood Transfusion, 28(2), 77-81.
https://doi.org/10.1007/s12288-011-0107-x
13. Borna, S., Borna, H., & Khazardoost, S. (2006). Maternal and neonatal outcomes in pregnant women with immune thrombocytopenic purpura. Arch Iran Med, 9(2), 115-8.
14. Chauhan, V., Gupta, A., Mahajan, N., Vij, A., Kumar, R., & Chadda, A. (2016). Maternal and fetal outcome among pregnant women presenting with thrombocytopenia. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2736-2743.
https://doi.org/10.18203/2320-1770.ijrcog20162658
15. Webert, K. E., Mittal, R., Sigouin, C., Heddle, N. M., & Kelton, J. G. (2003). A retrospective 11-year analysis of obstetric patients with idiopathic thrombocytopenic Purpura. Blood, 102(13), 4306-4311.
https://doi.org/10.1182/blood-2002-10-3317
16. Verma, A. R., Sood, A. K., Prabha, J., & Kumar, A. (2025). PREVALENCE OF THROMBOCYTOPENIA IN PREGNANCY AND ITS FETOMATERNAL OUTCOME. International Journal of Medicine & Public Health, 15(2).
17. TAŞ, B., & GÜNENC, O. (2022). Maternal and fetal outcomes of gestational Thrombocytopenia. Düzce Tıp Fakültesi Dergisi, 24(3), 282-286.
https://doi.org/10.18678/dtfd.1162645
18. Mumtaz, H., Danish, R., Yousaf, T., Sehgal, S., Jawad, A., & Ali Haider, S. M. (2023). Frequency and outcome of pregnant females presenting with Thrombocytopenia at a tertiary care hospital. Cureus.
https://doi.org/10.7759/cureus.49466
19. Chauhan, M., Chaudhary, S., Mehta, K., Malhotra, V., Nanda, S., & Rani, V. (2021). A prospective study to evaluate the role of maternal thrombocytopenia on maternal and fetal outcome. International Journal of Clinical Obstetrics and Gynaecology, 5(2), 127-133.
https://doi.org/10.33545/gynae.2021.v5.i2c.876
20. Khursheed, S., Sameen, D., Farhat, D., & A. Dar, S. (2022). Effects of maternal Thrombocytopenia on pregnancy outcome: A prospective observational study. Journal of Advances in Medicine and Medical Research, 1-7.
https://doi.org/10.9734/jammr/2022/v34i431279
21. Harde, M., Bhadade, R., DeSouza, R., & Jhingan, M. (2019). Thrombocytopenia in pregnancy nearing term: A clinical analysis. Indian Journal of Critical Care Medicine, 23(11), 503-508.
https://doi.org/10.5005/jp-journals-10071-23277
22. Chauhan, V., Gupta, A., Mahajan, N., Vij, A., Kumar, R., & Chadda, A. (2016). Maternal and fetal outcome among pregnant women presenting with thrombocytopenia. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2736-2743.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Indus Journal of Bioscience Research
This work is licensed under a Creative Commons Attribution 4.0 International License.
