A Comparative Study of Adult Appendicitis Score with Alvarado Score in the Diagnosis of Acute Appendicitis
DOI:
https://doi.org/10.70749/ijbr.v3i8.2937Keywords:
Acute Appendicitis, Adult Appendicitis Score, Sensitivity.Abstract
Introduction: For individuals suspected of having acute appendicitis, clinical evaluation based on a history and physical examination has been the main diagnostic approach. Although a number of diagnostic methods, such as imaging modalities and biochemical assays, have been developed, advanced diagnostic testing has not improved the detection of acute appendicitis. This diagnostic difficulty has led to the need for objective techniques of using scoring systems to evaluate those who may have acute appendicitis. Methodology: The study comprised 180 patients, aged 20 to 60 years presenting with suspected acute appendicitis undergoing appendectomy. Participants in this study were excluded if they had an appendicular mass or abscess, were pregnant, had undergone a laparotomy, had had an appendectomy, or had Koch's abdomen or inflammatory bowel disease. The cutoff point for a higher risk or probability/positive test of acute appendicitis was defined as an Alvarado scale score of ≥ 7 or higher. The cutoff point for a high risk or probability/positive test of acute appendicitis was defined as an Adult Appendicitis Score of ≥ 11 or above. The diagnostic accuracy of Alvarado and AAS was computed by comparing the histopathological results with the preoperative scores. Results: Acute appendicitis was diagnosed with a sensitivity of 93.85% Adult Appendicitis Score, a specificity of 80.0%, a PPV of 92.42%, an NPV of 83.33%, and a diagnostic accuracy of 90.0%. Acute appendicitis was diagnosed with a sensitivity of 90.72% alvardo score, a specificity of 72.0%, a PPV of 89.31%, an NPV of 73.47%, and a diagnostic accuracy of 85.0%. Conclusion: For the precise diagnosis of acute appendicitis, the Adult Appendicitis Score offers higher sensitivity and specificity.
Downloads
References
1. Wickramasinghe, D. P., Xavier, C., & Samarasekera, D. N. (2021). The worldwide epidemiology of acute appendicitis: An analysis of the global health data exchange dataset. World Journal of Surgery, 45(7), 1999-2008.
https://doi.org/10.1007/s00268-021-06077-5
2. Taghipour, A., Olfatifar, M., Javanmard, E., Norouzi, M., Mirjalali, H., & Zali, M. R. (2020). The neglected role of Enterobius vermicularis in appendicitis: A systematic review and meta-analysis. PLOS ONE, 15(4), e0232143.
https://doi.org/10.1371/journal.pone.0232143
3. Khudhar, H. E., & Jasim, D. M. (2023). Accuracy of diagnostic scales of acute appendicitis: Alvarado, RIPASA and AIR in comparison to histopathology. JMSP, 8(4), 256-73.
https://www.aafp.org/pubs/afp/issues/2018/0701/p25.html
4. Snyder MJ, Guthrie M, Cagle S. Acute appendicitis: efficient diagnosis and management. Am Fam Physician. 2018;98(1):25–33.
5. Gebreselassie, H., Zeleke, H., & Ashebir, D. (2023). Diagnosis of acute appendicitis: A cross-sectional study on Alvarado’s score from a low income country. Open Access Emergency Medicine, 15, 253-258.
https://doi.org/10.2147/oaem.s410119
6. Al Awayshih, M. M., Nofal, M. N., & Yousef, A. J. (2019). Evaluation of Alvarado score in diagnosing acute appendicitis. The Pan African Medical Journal, 34, 15.
7. Pifeleti, S., Hansell, D., & Kaspar, A. (2022). Sensitivity and specificity of the Alvarado score for the timely differential diagnosis of acute appendicitis for a case series in Samoa. Annals of Medicine & Surgery, 73.
https://doi.org/10.1016/j.amsu.2021.103219
8. Sammalkorpi, H. E., Mentula, P., Savolainen, H., & Leppäniemi, A. (2017). The introduction of adult appendicitis score reduced negative appendectomy rate. Scandinavian Journal of Surgery, 106(3), 196-201.
https://doi.org/10.1177/1457496916683099
9. Meena, R., Sharma, A. K., Kalwaniya, D. S., Tolat, A., Tyagi, G., Rohith, V. N., & Gurivelli, P. K. (2023). Evaluation of diagnostic accuracy of Alvarado, appendicitis inflammatory response and adult appendicitis scoring system in diagnosing acute appendicitis: A prospective cohort study. JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH.
https://doi.org/10.7860/jcdr/2023/60480.17409
10. Elsherbiny, M. W., Emile, S. H., Abdelnaby, M., Khafagy, W., & Elshobaky, A. (2020). Assessment of the diagnostic accuracy of alvarado scoring system combined with focused ultrasound in the diagnosis of acute appendicitis. Journal of British Surgery, 107(12), e594-e595.
https://doi.org/10.1002/bjs.12037
11. Deb, S., Yagnik, V. D., Garg, P., Bhattacharya, K., & Dawka, S. (2022). A comparative study between Alvarado score and adult appendicitis score in patients with right lower quadrant pain for diagnosing acute appendicitis. Global Journal of Medical, Pharmaceutical, and Biomedical Update, 17, 21.
https://doi.org/10.25259/gjmpbu_32_2022
12. O'Connell, P. R., McCaskie, A. W., & Sayers, R. D. (2022). Bailey & Love's short practice of surgery.
https://doi.org/10.1201/9781003106852
13. Mukhtar, A., Saeed, B., Awais, M., Shahid, J., Faiz, M. S., & Jalil, M. (2024). Comparison of diagnostic accuracy of alvarado score and ripasa scoring system in diagnosis of acute appendicitis. NORTHWEST JOURNAL OF MEDICAL SCIENCES, 3(4), 13-18.
https://doi.org/10.69723/njms.03.04.0429
14. Sammalkorpi, H. E., Mentula, P., & Leppäniemi, A. (2014). A new adult appendicitis score improves diagnostic accuracy of acute appendicitis - a prospective study. BMC Gastroenterology, 14(1).
https://doi.org/10.1186/1471-230x-14-114
15. Podda, M., Pellino, G., Coccolini, F., Gerardi, C., Di Saverio, S., Pata, F., Ielpo, B., Virdis, F., Damaskos, D., Gourgiotis, S., Poillucci, G., Pacella, D., Jayant, K., Agresta, F., Sartelli, M., Leppaniemi, A., Kluger, Y., Catena, F., & Pisanu, A. (2021). Compliance with evidence-based clinical guidelines in the management of acute biliary pancreatitis: The MANCTRA-1 study protocol. Updates in Surgery, 73(5), 1757-1765.
https://doi.org/10.1007/s13304-021-01118-z
16. Acharya, A., Markar, S. R., Ni, M., & Hanna, G. B. (2016). Biomarkers of acute appendicitis: Systematic review and cost–benefit trade-off analysis. Surgical Endoscopy, 31(3), 1022-1031.
https://doi.org/10.1007/s00464-016-5109-1
17. Chae, M. S., Hong, C. K., Ha, Y. R., Chae, M. K., Kim, Y. S., Shin, T. Y., & Ahn, J. H. (2017). Can clinical scoring systems improve the diagnostic accuracy in patients with suspected adult appendicitis and equivocal preoperative computed tomography findings? Clinical and Experimental Emergency Medicine, 4(4), 214-221.
https://doi.org/10.15441/ceem.16.168
18. Shah, A. A., Al-Zoubi, R. M., Al-Qudimat, A. R., Amine Rejeb, M., Kumari Ojha, L., Abdulzem, S., Qadir, K., Sameer, S., Zarour, A., & Said Ghali, M. (2022). Daytime versus nighttime laparoscopic appendectomy in term of complications and clinical outcomes: A retrospective study of 1001 appendectomies. Heliyon, 8(12), e11911.
https://doi.org/10.1016/j.heliyon.2022.e11911
19. Kabir, S. M., Bucholc, M., Walker, C., Sogaolu, O. O., Zeeshan, S., & Sugrue, M. (2020). Quality outcomes in appendicitis care: Identifying opportunities to improve care. Life, 10(12), 358.
https://doi.org/10.3390/life10120358
20. Capoglu, R., Gonullu, E., Bayhan, Z., Coskun, M., Harmantepe, T., & Kucuk, F. (2022). Comparison of scoring systems regarding the gender as a parameter with the traditional scoring systems for predicting appendicitis. Updates in Surgery, 74(3), 1035-1042.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Indus Journal of Bioscience Research

This work is licensed under a Creative Commons Attribution 4.0 International License.