Evaluation of Serum Urea and Creatinine as Predictive Biomarkers of Renal Dysfunction in Diabetes Mellitus
DOI:
https://doi.org/10.70749/ijbr.v4iS1.3121Keywords:
Serum urea, Serum creatinine, Renal function, eGFR, kidney disease.Abstract
Diabetes mellitus is a persistent metabolism disease, which may have severe complications, especially the damaged functioning of the kidney. It is critical to keep renal biomarkers monitored to timely identify kidney impairment. The study was conducted to examine the value of serum urea and creatinine as early biochemicals markers of diabetes linked to renal stress. The cross-sectional study was a comparative study that involved a sample of 139 participants, who were carefully selected using non-probability convenience sampling. Blood tests, serum urea and creatinine were done for both groups. A t-test was used to estimate statistical significance by the use of an independent sample. The serum urea and creatinine were significantly higher among diabetic patients, and eGFR levels were reduced relative to non-diabetic patients, which implied the poor renal functioning (p < 0.001. Kidney functionality is greatly affected in diabetes. Early prevention and detection of renal complications may be performed with the help of regular observation of serum urea and creatinine.
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