Determinants of Adherence to Medical Therapy in Pregnant Patients with Systemic Lupus Erythematosus

Bushra; Muhammad Zahid Hussain; Syeda Kinza Bukhari; Irfan Najam Sheen; Muhammad Shahid Khan; Zoha Hashmi

doi:10.70749/ijbr.v3i4.1080

Authors

Bushra Department of Medicine, Combined Military Hospital (CMH), Multan, Pakistan
Muhammad Zahid Hussain Department of Rheumatology, Combined Military Hospital (CMH) Multan, Pakistan
Syeda Kinza Bukhari Department of Medicine, Combined Military Hospital (CMH) Multan, Pakistan
Irfan Najam Sheen Department of Medicine, Combined Military Hospital (CMH) Multan, Pakistan
Muhammad Shahid Khan Department of Medicine, HITEC- Institute of Medical Sciences Taxila Cantt, Pakistan
Zoha Hashmi Department of Medicine, Combined Military Hospital (CMH) Multan, Pakistan

DOI:

https://doi.org/10.70749/ijbr.v3i4.1080

Keywords:

Systemic Lupus Erythematosus, Medication adherence, Pregnancy, Patient-provider communication

Abstract

Objective: To assess the determinants of adherence to medical therapy among pregnant patients with Systemic Lupus Erythematosus. Study Design: Cross-sectional study. Duration and Place of Study: The study was conducted from August 2023 to February 2024 at CMH Multan. Methodology: A total of 196 pregnant women diagnosed with SLE were enrolled. Data were collected using a structured interview schedule and the 8-item Morisky Medication Adherence Scale (MMAS-8). Participants were assessed for socio-demographic factors, disease-related characteristics, and factors influencing adherence. Medication adherence was evaluated in relation to educational level, disease awareness, family support, and interaction with healthcare providers. Results: The mean age of participants was 29.05 ± 6.01 years, with a higher prevalence in rural areas (68.4%). Results showed that 91.3% of patients were confident in adhering to their medication regimen, but only 74% had satisfactory patient-provider communication. Conclusion: Key determinants such as education, disease awareness, communication with healthcare providers, and family support significantly affect medication adherence in pregnant women with SLE.

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