Risk Factors of Surgical Site Infections in Cesarean Sections in Lady Reading Hospital Peshawar
DOI:
https://doi.org/10.70749/ijbr.v3i4.2233Keywords:
Cesarean section, Surgical site infection, Risk factors, Preeclampsia, Prolonged rupture of membranes, Meconium.Abstract
Background: Surgical site infections are a major source of morbidity following cesarean deliveries, increasing hospital stays, healthcare costs, and maternal discomfort. Identifying patient-related and clinical risk factors is crucial for early intervention and prevention, particularly in regions with limited healthcare resources. Objective: To determine the risk factors of surgical site infections in patients undergoing cesarean sections in Lady Reading Hospital Peshawar. Study Design: Cross-sectional study. Duration and Place of Study: The research was conducted in the Department of Obstetrics and Gynecology, Lady Reading Hospital, Peshawar, from July 2024 to December 2024. Methodology: A total of 177 women aged 18–40 years who developed surgical site infections after cesarean section were included. Sampling was performed using a non-probability consecutive technique. Risk factors assessed included prolonged rupture of membranes (>20 hours), preeclampsia, and meconium-stained amniotic fluid. Data were analyzed in SPSS version 25, with associations tested using Chi-square or Fisher’s exact test at a 5% significance threshold. Results: Prolonged rupture of membranes was observed in 26.0% of cases, preeclampsia in 19.2%, and meconium-stained liquor in 5.6%. Hypertension showed a strong association with preeclampsia (p<0.001), while no significant associations were found for other demographic or clinical factors. Conclusion: Hypertensive disorders, particularly preeclampsia, remain key contributors to surgical site infections in cesarean sections, underscoring the need for vigilant monitoring and targeted preventive strategies.
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1. Gomaa K, Abdelraheim AR, El Gelany S, Khalifa EM, Yousef AM, Hassan H. Incidence, risk factors and management of post cesarean section surgical site infection in a tertiary hospital in Egypt: a five year retrospective study. BMC Pregnancy Childbirth. 2021;21(1):634.
https://doi.org/10.1186/s12884-021-04054-3.
2. Kawakita T, Landy HJ. Surgical site infections after cesarean delivery: epidemiology, prevention and treatment. Matern Health Neonatol Perinatol. 2017;3:12.
https://doi.org/10.1186/s40748-017-0051-3.
3. Bucataru A, Balasoiu M, Ghenea AE, Zlatian OM, Vulcanescu DD, Horhat FG, et al. Factors contributing to surgical site infections: a comprehensive systematic review of etiology and risk factors. Clin Pract. 2023;14(1):52-68.
https://doi.org/10.3390/clinpract14010006.
4. Shi M, Chen L, Ma X, Wu B. The risk factors and nursing countermeasures of sepsis after cesarean section: a retrospective analysis. BMC Pregnancy Childbirth. 2022;22(1):696.
https://doi.org/10.1186/s12884-022-04982-8.
5. Rezaei AR, Zienkiewicz D, Rezaei AR. Surgical site infections: a comprehensive review. J Trauma Inj. 2025;38(2):71-81.
https://doi.org/10.20408/jti.2025.0019.
6. He X, Li D, Sun T, Dai Q, Hu M, Zhu Z, et al. Risk factors for surgical site infection after cesarean delivery in a rural area in China: a case-controlled study. Ann Med Surg (Lond). 2021;72:103110.
https://doi.org/10.1016/j.amsu.2021.103110.
7. Shacho E, Yilma D, Goshu AT, Ambelu A. Incidence and risk factors of surgical site infection following cesarean section: a prospective cohort study at Jimma University Medical Center. BMC Infect Dis. 2025;25(1):457.
https://doi.org/10.1186/s12879-025-10857-y.
8. Chang KJ, Seow KM, Chen KH. Preeclampsia: recent advances in predicting, preventing, and managing the maternal and fetal life-threatening condition. Int J Environ Res Public Health. 2023;20(4):2994.
https://doi.org/10.3390/ijerph20042994.
9. Ronghe V, Modak A, Gomase K, Mahakalkar MG. From prevention to management: understanding postoperative infections in gynaecology. Cureus. 2023;15(10):e46319.
https://doi.org/10.7759/cureus.46319.
10. Adane A, Gedefa L, Eyeberu A, Tesfa T, Arkew M, Tsegaye S, et al. Predictors of surgical site infection among women following cesarean delivery in eastern Ethiopia: a prospective cohort study. Ann Med Surg (Lond). 2023;85(4):738-45.
https://doi.org/10.1097/MS9.0000000000000411.
11. Jahan FI, Begum F, Islam F, Pervin S, Goodman A. Risk factors for wound infection following caesarean section: a case control study from Sir Salimullah Medical College & Mitford Hospital in Dhaka, Bangladesh. J Obstet Gynecol. 2019;9(6):904-13.
12. Abd-El-Kareem HF, Salman AD, Hameed BM. The risk of post-cesarean surgical site infection in meconium-stained amniotic fluid. J Am Med Sci Res. 2025;4(1):1-10.
https://doi.org/10.51470/AMSR.2024.04.01.04.
13. Fatima N, Ellahi A, Shawita. Surgical site infection and factors responsible for it after emergency cesarean section. J Surg Pakistan. 2020;25(1):27-30.
14. Iran Nezhad Deljavan F, Mohammad Jafari R, Karegarzadeh E, Nikbakht R. Evaluation of surgical site infections after cesarean section and its related factors in women referring to Emam Khomeini Hospital, Ahvaz, Iran 2021–2022. J Obstet Gynecol Cancer Res. 2025;10(5):368-74.
https://doi.org/10.30699/10gcr.10.5.368.
15. Tebeu PM, Kamdem A, Ngou-Mve-Ngou JP, et al. Risk factors for surgical site infections after caesarean section at Yaounde, Cameroon. Int J Reprod Contracept Obstet Gynecol. 2021;10(11):4048-51.
https://doi.org/10.18203/2320-1770.ijrcog20214309
16. Dereje T, Sharew T, Hunde L. The prevalence of meconium stained amniotic fluid and its associated factors among women who gave birth at term in Adama Hospital Medical College, Ethiopia. Ethiop J Health Sci. 2023;33(2):219-26.
https://doi.org/10.4314/ejhs.v33i2.6
17. He X, Li D, Sun T, et al. Risk factors for surgical site infection after cesarean delivery in a rural area: a case-control study. Ann Med Surg. 2021;72:103110.
https://doi.org/10.1016/j.amsu.2021.103110.
18. Guanche Garcell H, Desdin Rodriguez RM, Erice Rivero TS, et al. Risk factors for surgical site infection after cesarean section in a multinational population. Hosp Pract Res. 2024;9(4):544-8.
https://doi.org/10.30491/hpr.2024.493615.1461.
19. Zaineb S, Akbar A, Ikram M, et al. Incidence and risk factors for maternal surgical site infection after cesarean section. Prof Med J. 2021;28(10):1495-500.
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