Obstetric Outcome in Women with First Trimester Vaginal Bleeding

Authors

  • Maha Shafqat Department of Gynaecology & Obstetrics, Central Park Teaching Hospital, Lahore, Punjab, Pakistan.
  • Nayyer Sultana Department of Gynaecology & Obstetrics, Central Park Teaching Hospital, Lahore, Punjab, Pakistan.
  • Faiza Khan Department of Gynaecology & Obstetrics, Chaudhary Muhammad Akram Teaching Hospital, Lahore, Punjab, Pakistan.
  • Uzma Malik Department of Gynaecology & Obstetrics, Iqra Hospital, Lahore, Punjab, Pakistan.
  • Tehreema Khan Department of Gynaecology & Obstetrics, Chaudhary Muhammad Akram Teaching Hospital, Lahore, Punjab, Pakistan.
  • Tayyaba Majeed Department of Gynaecology & Obstetrics, Central Park Teaching Hospital, Lahore, Punjab, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i4.2482

Keywords:

First-trimester Bleeding, Pregnancy-induced Hypertension, Preterm Delivery, Placental Abruption, Neonatal Outcomes.

Abstract

Background: First-trimester vaginal bleeding is one of the most common complications of early pregnancy, affecting nearly one in four women. Objective: To assess the obstetric and neonatal outcomes in women presenting with first-trimester vaginal bleeding and to evaluate the relationship between bleeding severity and adverse pregnancy outcomes. Methodology: This Cross-sectional study was conducted at the Department of Obstetrics and Gynecology, Central Park hospital from 15th September, 2023 to 15th march, 2024Two hundred pregnant women with first-trimester vaginal bleeding were enrolled using random sampling. Pregnant women aged 20–40 years presenting with vaginal bleeding during the first trimester were included. Demographic data, clinical findings, and severity of bleeding were recorded. Ultrasonography was performed to assess pregnancy viability. Results: The mean age of participants was 27.97 ± 4.06 years, and the mean parity was 1.90 ± 0.65. PIH was the most frequent maternal complication (16.5%), followed by oligohydramnios (9.5%) and placental abruption (9.0%). Preterm deliveries occurred in 20% of cases. Neonatal outcomes were generally favorable, with a mean birth weight of 3.10 ± 1.89 kg and no stillbirths, though 18.5% required NICU admission.  Conclusion: It is concluded that first-trimester vaginal bleeding is an important predictor of adverse obstetric outcomes. Moderate to heavy bleeding is significantly associated with PIH, placental abruption, and preterm delivery.

Downloads

Download data is not yet available.

References

1. Al‐Memar, M., Vaulet, T., Fourie, H., Nikolic, G., Bobdiwala, S., Saso, S., Farren, J., Pipi, M., Van Calster, B., De Moor, B., Stalder, C., Bennett, P., Timmerman, D., & Bourne, T. (2019). Early‐pregnancy events and subsequent antenatal, delivery and neonatal outcomes: Prospective cohort study. Ultrasound in Obstetrics & Gynecology, 54(4), 530-537.

https://doi.org/10.1002/uog.20262

2. Hendriks, E., MacNaughton, H., & MacKenzie, M. C. (2019). First trimester bleeding: evaluation and management. American family physician, 99(3), 166-174.

https://www.aafp.org/pubs/afp/issues/2019/0201/p166.html

3. Mouri MI, Hall H, Rupp TJ. (2023). Threatened Abortion. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing.

4. Nynas, J., Narang, P., Kolikonda, M. K., & Lippmann, S. (2015). Depression and anxiety following early pregnancy loss. The Primary Care Companion For CNS Disorders.

https://doi.org/10.4088/pcc.14r01721

5. Naurin, R., Tahseen, S., & Naurin, R. (2015). Maternal outcome in women with threatened miscarriage. Methodology, 31.

6. Birindwa, E. K., Sindayirwanya, J., & Harerimana, S. (2020). Pronostic de la grossesse qui saigne AU premier trimestre: A propos de 239 cas colligés AU centre hospitalo-universitaire de Kamenge, Bujumbura. Pan African Medical Journal, 35.

https://doi.org/10.11604/pamj.2020.35.111.20413

7. Liu, S., Yu, L., Wu, Q., Cui, H., Lin, X., & Wang, W. (2021). Study on the correlation between vaginal bleeding in first trimester and preterm birth: A birth cohort study in Lanzhou, China. Journal of Obstetrics and Gynaecology Research, 47(6), 1997-2004.

https://doi.org/10.1111/jog.14750

8. Bever, A. M., Pugh, S. J., Kim, S., Newman, R. B., Grobman, W. A., Chien, E. K., Wing, D. A., Li, H., Albert, P. S., & Grantz, K. L. (2018). Fetal growth patterns in pregnancies with first-trimester bleeding. Obstetrics & Gynecology, 131(6), 1021-1030.

https://doi.org/10.1097/aog.0000000000002616

9. John, S., Sreedevi, N. P. S. B., & John, R. (2022). Threatened Miscarriage and Adverse Fetomaternal Outcome Late in Pregnancy—A Prospective Study. Journal of South Asian Federation of Obstetrics and Gynaecology, 14(4), 387-392.

https://doi.org/10.5005/jp-journals-10006-2100

10. Siddu, S., Dhama, V., Chaudhary, R., & Singh, S. (2022). The study of outcome of pregnancy with first trimester vaginal bleeding and its complications. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 11(4), 1150.

https://doi.org/10.18203/2320-1770.ijrcog20220896

11. Choudhury, S., Dubey, K., Sengar, B. S., & Chetiwar, S. (2024). First-trimester vaginal bleeding and adverse obstetric outcomes in a semi-urban population of India: A prospective observational study. Cureus.

https://doi.org/10.7759/cureus.64784

12. Naskar, A., Chowdhury, R., Saha, P. K., & Das, R. K. (2022). Evaluation of pregnancy outcome in women with first trimester vaginal bleeding: A longitudinal study at a tertiary care hospital, Kolkata, India. JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH.

https://doi.org/10.7860/jcdr/2022/57184.16906

13. Kamble, P. D., Bava, A., Shukla, M., & Nandanvar, Y. S. (2017). First trimester bleeding and pregnancy outcome. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 6(4), 1484.

https://doi.org/10.18203/2320-1770.ijrcog20171414

14. Ibrahim, W., Gebriel, M., & Abdelmoaty, M. (2022). Pregnancy outcome in women presenting with 1st trimester vaginal bleeding. International Journal of Medical Arts, 4(8), 2586-2591.

https://doi.org/10.21608/ijma.2022.154739.1492

15. Siddu, S., Dhama, V., Chaudhary, R., & Singh, S. (2022). The study of outcome of pregnancy with first trimester vaginal bleeding and its complications. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 11(4), 1150.

https://doi.org/10.18203/2320-1770.ijrcog20220896

16. Manohar, N., & Ramanujam, S. L. (2025). Feto-Maternal Outcomes in Antenatal Women with First-Trimester Vaginal Bleeding: A Retrospective Observational Study. Jneonatalsurg.com.

https://doi.org/10.52783/jns.v14.3846

17. Choudhury, S., Dubey, K., Sengar, B. S., & Chetiwar, S. (2024). First-trimester vaginal bleeding and adverse obstetric outcomes in a semi-urban population of India: A prospective observational study. Cureus.

https://doi.org/10.7759/cureus.64784

18. Al‐Memar, M., Vaulet, T., Fourie, H., Nikolic, G., Bobdiwala, S., Saso, S., Farren, J., Pipi, M., Van Calster, B., De Moor, B., Stalder, C., Bennett, P., Timmerman, D., & Bourne, T. (2019). Early‐pregnancy events and subsequent antenatal, delivery and neonatal outcomes: Prospective cohort study. Ultrasound in Obstetrics & Gynecology, 54(4), 530-537.

https://doi.org/10.1002/uog.20262

19. Hendriks, E., MacNaughton, H., & MacKenzie, M. C. (2019). First trimester bleeding: evaluation and management. American family physician, 99(3), 166-174.

https://www.aafp.org/pubs/afp/issues/2019/0201/p166.html

20. Mouri MI, Hall H, Rupp TJ. (2023). Threatened Abortion. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing.

21. Nynas, J., Narang, P., Kolikonda, M. K., & Lippmann, S. (2015). Depression and anxiety following early pregnancy loss. The Primary Care Companion For CNS Disorders.

https://doi.org/10.4088/pcc.14r01721

Downloads

Published

2025-04-30

How to Cite

Shafqat, M., Sultana, N., Khan, F., Malik, U., Khan, T., & Majeed, T. (2025). Obstetric Outcome in Women with First Trimester Vaginal Bleeding. Indus Journal of Bioscience Research, 3(4), 1151-1154. https://doi.org/10.70749/ijbr.v3i4.2482