Frequency of Low Heart Rate Reserve and Mean Arterial Pressure in Patients with Positive Exercise Tolerance Test

Authors

  • Nida Batool Liaquat National Hospital & Medical College, Karachi, Sindh, Pakistan.
  • Kaleemullah Shaikh Liaquat National Hospital & Medical College, Karachi, Sindh, Pakistan.
  • Faryal Fatima Liaquat National Hospital & Medical College, Karachi, Sindh, Pakistan.
  • Sadia Abubakar Liaquat National Hospital & Medical College, Karachi, Sindh, Pakistan.
  • Fizzah Jawed Liaquat National Hospital & Medical College, Karachi, Sindh, Pakistan.
  • Tooba Usama Liaquat National Hospital & Medical College, Karachi, Sindh, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i4.2977

Keywords:

Low Heart Rate Reserve, Mean Arterial Blood Pressure, Positive Exercise Tolerance Test, Coronary Angiography.

Abstract

Background: An exercise treadmill test can detect the presence of myocardial ischemia and changes in heart rate and blood pressure (BP) during exercise.  Objective: To assess the frequency of low heart rate reserve and mean arterial blood pressure in patients with positive exercise tolerance test who underwent coronary angiography, at a tertiary care hospital. Material and Methods: This cross-sectional study included 246 patients with positive exercise tolerance test. Low heart rate reserve (<50 bpm) and mean arterial pressure were calculated. Mean comparisons were conducted utilising independent t-tests and Mann-Whitney U tests. Odds ratio were calculated using logistic regression A p-value of 0.05 or below was considered statistically significant. Results: The male patients were 77.2%. Heart rate reserve was significantly associated with older age (p<0.001), lower maximal (p<0.001) and resting heart rates (p<0.001), reduced heart rate reserve (p<0.001), lower mean arterial pressure (p<0.001), and lower prevalence of dyslipidaemia (p=0.040). Younger age and dyslipidaemia were protective against low heart rate reserve. BMI categories had no statistically significant correlation with poor heart rate reserve. Mean arterial pressure was significantly higher in younger individuals (p=0.007) and those with dyslipidaemia (p=0.040). Conclusion: Total 22.4% patients with heart rate reserve were observed. Median of Mean Atrial Pressure (mmHg)was 103.00. A strong association of CAD and heart rate reserves was observed with mean arterial pressure. Significant heart rate variations were observed in affected individuals, and age and dyslipidaemia influenced mean arterial pressure..

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Published

2025-04-30

How to Cite

Batool, N., Shaikh, K., Fatima, F., Abubakar, S., Jawed, F., & Usama, T. (2025). Frequency of Low Heart Rate Reserve and Mean Arterial Pressure in Patients with Positive Exercise Tolerance Test. Indus Journal of Bioscience Research, 3(4), 1305-1312. https://doi.org/10.70749/ijbr.v3i4.2977